The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.
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| Title: | The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults. |
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| Authors: | Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Dadi PK; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Kim J; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Department of Chemistry, Vanderbilt University, Nashville, United States., Dickerson MT; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Behera S; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Dobson JR; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States., Shrestha S; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Cartailler JP; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Sampson L; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States., Magnuson MA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Center for Stem Cell Biology, Vanderbilt University, Nashville, United States.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, United States., Jacobson DA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States. |
| Source: | ELife [Elife] 2024 May 03; Vol. 12. Date of Electronic Publication: 2024 May 03. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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