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Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's disease.

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Title: Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's disease.
Authors: Fang P; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. phoen.f@gmail.com., Yu LW; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Espey H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Agirman G; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Kazmi SA; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Li K; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Deng Y; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Lee J; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hrncir H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Romero-Lopez A; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA., Arnold AP; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hsiao EY; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.
Source: Communications biology [Commun Biol] 2024 May 15; Vol. 7 (1), pp. 570. Date of Electronic Publication: 2024 May 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Fang+P%22">Fang P</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. phoen.f@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yu+LW%22">Yu LW</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Espey+H%22">Espey H</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Agirman+G%22">Agirman G</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Kazmi+SA%22">Kazmi SA</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.<br /><searchLink fieldCode="AU" term="%22Deng+Y%22">Deng Y</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hrncir+H%22">Hrncir H</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Romero-Lopez+A%22">Romero-Lopez A</searchLink>; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Arnold+AP%22">Arnold AP</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hsiao+EY%22">Hsiao EY</searchLink>; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. ehsiao@g.ucla.edu.
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