Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas.
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| Title: | Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas. |
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| Authors: | Arrieta VA; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; PECEM, Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico., Gould A; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Kim KS; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Habashy KJ; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Dmello C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Vázquez-Cervantes GI; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Palacín-Aliana I; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Deparment of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., McManus G; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Amidei C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Gomez C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Dhiantravan S; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Chen L; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Zhang DY; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Saganty R; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Cholak ME; Department of Medicine, Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Pandey S; Department of Medicine, Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., McCord M; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Deparment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., McCortney K; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Castro B; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Ward R; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Muzzio M; Life Sciences Group, IIT Research Institute, Chicago, IL, USA., Bouchoux G; Carthera, Lyon, France., Desseaux C; Carthera, Lyon, France., Canney M; Carthera, Lyon, France., Carpentier A; Sorbonne Université, Inserm, CNRS, UMR S 1127, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Service de Neurochirurgie, Paris, France., Zhang B; Department of Medicine, Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Miska JM; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Lesniak MS; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Horbinski CM; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Lukas RV; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Stupp R; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Department of Medicine, Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Lee-Chang C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. catalina.leechang@northwestern.edu.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. catalina.leechang@northwestern.edu., Sonabend AM; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. adam.sonabend@northwestern.edu.; Northwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. adam.sonabend@northwestern.edu. |
| Source: | Nature communications [Nat Commun] 2024 Jun 06; Vol. 15 (1), pp. 4698. Date of Electronic Publication: 2024 Jun 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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