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Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants.

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Title: Deep mutational scanning quantifies DNA binding and predicts clinical outcomes of PAX6 variants.
Authors: McDonnell AF; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Plech M; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Livesey BJ; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Gerasimavicius L; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Owen LJ; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Hall HN; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., FitzPatrick DR; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Marsh JA; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK., Kudla G; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK. gkudla@gmail.com.
Source: Molecular systems biology [Mol Syst Biol] 2024 Jul; Vol. 20 (7), pp. 825-844. Date of Electronic Publication: 2024 Jun 07.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22McDonnell+AF%22">McDonnell AF</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Plech+M%22">Plech M</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Livesey+BJ%22">Livesey BJ</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Gerasimavicius+L%22">Gerasimavicius L</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Owen+LJ%22">Owen LJ</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Hall+HN%22">Hall HN</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22FitzPatrick+DR%22">FitzPatrick DR</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Marsh+JA%22">Marsh JA</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Kudla+G%22">Kudla G</searchLink>; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, EH4 2XU, UK. gkudla@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101235389%22">Molecular systems biology</searchLink> [Mol Syst Biol] 2024 Jul; Vol. 20 (7), pp. 825-844. <i>Date of Electronic Publication: </i>2024 Jun 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101235389 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-4292 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217444292%22">17444292 </searchLink><i>NLM ISO Abbreviation: </i>Mol Syst Biol <i>Subsets: </i>MEDLINE
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