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Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2.

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Title: Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2.
Authors: Tsang ES; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Dhawan MS; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Pacaud R; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Thomas S; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Grabowsky J; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Wilch L; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Karipineni S; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Kelley RK; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Ko AH; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Collisson E; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Chapman JS; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Ueda S; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Bergsland EK; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA., Munster P; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.
Source: JCO precision oncology [JCO Precis Oncol] 2024 Jun; Vol. 8, pp. e2300494.
Publication Type: Journal Article; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthetic Lethality Beyond BRCA: A Phase I Study of Rucaparib and Irinotecan in Metastatic Solid Tumors With Homologous Recombination-Deficiency Mutations Beyond BRCA1/2.
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  Data: <searchLink fieldCode="AU" term="%22Tsang+ES%22">Tsang ES</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Dhawan+MS%22">Dhawan MS</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Pacaud+R%22">Pacaud R</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Thomas+S%22">Thomas S</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Grabowsky+J%22">Grabowsky J</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Wilch+L%22">Wilch L</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Karipineni+S%22">Karipineni S</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Kelley+RK%22">Kelley RK</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Ko+AH%22">Ko AH</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Collisson+E%22">Collisson E</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Chapman+JS%22">Chapman JS</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Ueda+S%22">Ueda S</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Bergsland+EK%22">Bergsland EK</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Munster+P%22">Munster P</searchLink>; Division of Hematology and Oncology, University of California San Francisco, San Francisco, CA.
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  Data: <searchLink fieldCode="JN" term="%22101705370%22">JCO precision oncology</searchLink> [JCO Precis Oncol] 2024 Jun; Vol. 8, pp. e2300494.
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              Text: 2024 Jun
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