Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition.

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Title: Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition.
Authors: Bracken RC; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA., Davison LM; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Buehler DP; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Fulton ME; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Carson EE; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Sheng Q; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 3723, USA., Stolze LK; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 3723, USA., Guillermier C; Harvard Medical School, Boston, MA 02115, USA.; Center for NanoImaging, Cambridge MA 02115, USA.; Department of Medicine, Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA., Steinhauser ML; Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Brown JD; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Source: IScience [iScience] 2024 May 16; Vol. 27 (6), pp. 110011. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Bracken+RC%22">Bracken RC</searchLink>; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Davison+LM%22">Davison LM</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Buehler+DP%22">Buehler DP</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Fulton+ME%22">Fulton ME</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Carson+EE%22">Carson EE</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.<br /><searchLink fieldCode="AU" term="%22Sheng+Q%22">Sheng Q</searchLink>; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 3723, USA.<br /><searchLink fieldCode="AU" term="%22Stolze+LK%22">Stolze LK</searchLink>; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 3723, USA.<br /><searchLink fieldCode="AU" term="%22Guillermier+C%22">Guillermier C</searchLink>; Harvard Medical School, Boston, MA 02115, USA.; Center for NanoImaging, Cambridge MA 02115, USA.; Department of Medicine, Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Steinhauser+ML%22">Steinhauser ML</searchLink>; Aging Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.<br /><searchLink fieldCode="AU" term="%22Brown+JD%22">Brown JD</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2024 May 16; Vol. 27 (6), pp. 110011. <i>Date of Electronic Publication: </i>2024 May 16 (<i>Print Publication: </i>2024).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101724038 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-0042 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225890042%22">25890042 </searchLink><i>NLM ISO Abbreviation: </i>iScience <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2024 May 16
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