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Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.

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Title: Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.
Authors: Mastenbroek SE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. s.e.mastenbroek@amsterdamumc.nl., Vogel JW; Department of Clinical Sciences Malmö, Faculty of Medicine, SciLifeLab, Lund University, Lund, Sweden., Collij LE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Serrano GE; Banner Sun Health Research Institute, Sun City, AZ, USA., Tremblay C; Banner Sun Health Research Institute, Sun City, AZ, USA., Young AL; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK., Arce RA; Banner Sun Health Research Institute, Sun City, AZ, USA., Shill HA; Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA., Driver-Dunckley ED; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Mehta SH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Belden CM; Banner Sun Health Research Institute, Sun City, AZ, USA., Atri A; Banner Sun Health Research Institute, Sun City, AZ, USA.; Department of Neurology, Center for Mind/Brain Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA., Choudhury P; Banner Sun Health Research Institute, Sun City, AZ, USA., Barkhof F; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, UK., Adler CH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam University Medical Center location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Beach TG; Banner Sun Health Research Institute, Sun City, AZ, USA., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.
Source: Nature communications [Nat Commun] 2024 Jun 15; Vol. 15 (1), pp. 5133. Date of Electronic Publication: 2024 Jun 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mastenbroek+SE%22">Mastenbroek SE</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands. s.e.mastenbroek@amsterdamumc.nl.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. s.e.mastenbroek@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22Vogel+JW%22">Vogel JW</searchLink>; Department of Clinical Sciences Malmö, Faculty of Medicine, SciLifeLab, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Collij+LE%22">Collij LE</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Serrano+GE%22">Serrano GE</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Tremblay+C%22">Tremblay C</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Young+AL%22">Young AL</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Arce+RA%22">Arce RA</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Shill+HA%22">Shill HA</searchLink>; Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Driver-Dunckley+ED%22">Driver-Dunckley ED</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Mehta+SH%22">Mehta SH</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Belden+CM%22">Belden CM</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Atri+A%22">Atri A</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.; Department of Neurology, Center for Mind/Brain Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Choudhury+P%22">Choudhury P</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Barkhof+F%22">Barkhof F</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, The Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Adler+CH%22">Adler CH</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam University Medical Center location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Beach+TG%22">Beach TG</searchLink>; Banner Sun Health Research Institute, Sun City, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Jun 15; Vol. 15 (1), pp. 5133. <i>Date of Electronic Publication: </i>2024 Jun 15.
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