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The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program.

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Title: The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program.
Authors: Fagnan A; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.; MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital University of Oxford Oxford UK., Aid Z; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Baille M; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Drakul A; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland., Robert E; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Lopez CK; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Thirant C; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Lecluse Y; Gustave Roussy, Plateforme Imagerie et Cytométrie, Université Paris-Saclay, UMS AMMICA, INSERM US23, CNRS UMS 3655 Villejuif France., Rivière J; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Ignacimouttou C; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France., Salmoiraghi S; Department of Oncology and Hematology Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, FROM Research Foundation, Papa Giovanni XXIII Hospital Bergamo Italy., Anguita E; Hematology Department, Hospital Clínico San Carlos (HCSC), IML, IdISSC, Department of Medicine Universidad Complutense de Madrid (UCM) Madrid Spain., Naimo A; Gustave Roussy, Genomic Platform Université Paris-Saclay, UMS AMMICA, INSERM US23, CNRS UMS 3655 Villejuif France., Marzac C; Department of Hematology Leukemia Interception Program, Personalized Cancer Prevention Center, Gustave Roussy Villejuif France., Pflumio F; Equipe Labellisée Ligue Contre le Cancer Paris France.; Unité de Recherche (UMR)-E008 Stabilité Génétique, Cellules Souches et Radiations, Team Niche and Cancer in Hematopoiesis, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA) Université de Paris-Université Paris-Saclay Fontenay-aux-Roses France.; OPALE Carnot Institute, The Organization for Partnerships in Leukemia Paris France., Malinge S; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Telethon Kids Institute, Perth Children's Hospital Nedlands Australia., Wichmann C; Department of Transfusion Medicine, Cell Therapeutics and Haemostasis Ludwig-Maximilians-University of Munich Munich Germany., Huang Y; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland., Lobry C; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; INSERM U944, CNRS UMR7212 Institut de Recherche Saint Louis and Université de Paris Paris France., Chaumeil J; Université de Paris, Institut Cochin, INSERM, CNRS Paris France., Soler E; IGMM, University of Montpellier, CNRS, Montpellier, France & Université de Paris, Laboratory of Excellence GR-Ex Paris France., Bourquin JP; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland., Nerlov C; MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital University of Oxford Oxford UK., Bernard OA; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France., Schwaller J; Department of Biomedicine University Children's Hospital Beider Basel (UKBB), University of Basel Basel Switzerland., Mercher T; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.; OPALE Carnot Institute, The Organization for Partnerships in Leukemia Paris France.
Source: HemaSphere [Hemasphere] 2024 Jun 19; Vol. 8 (6), pp. e90. Date of Electronic Publication: 2024 Jun 19 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program.
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  Data: <searchLink fieldCode="AU" term="%22Fagnan+A%22">Fagnan A</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.; MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital University of Oxford Oxford UK.<br /><searchLink fieldCode="AU" term="%22Aid+Z%22">Aid Z</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Baille+M%22">Baille M</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Drakul+A%22">Drakul A</searchLink>; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland.<br /><searchLink fieldCode="AU" term="%22Robert+E%22">Robert E</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Lopez+CK%22">Lopez CK</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Thirant+C%22">Thirant C</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Lecluse+Y%22">Lecluse Y</searchLink>; Gustave Roussy, Plateforme Imagerie et Cytométrie, Université Paris-Saclay, UMS AMMICA, INSERM US23, CNRS UMS 3655 Villejuif France.<br /><searchLink fieldCode="AU" term="%22Rivière+J%22">Rivière J</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Ignacimouttou+C%22">Ignacimouttou C</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.<br /><searchLink fieldCode="AU" term="%22Salmoiraghi+S%22">Salmoiraghi S</searchLink>; Department of Oncology and Hematology Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, FROM Research Foundation, Papa Giovanni XXIII Hospital Bergamo Italy.<br /><searchLink fieldCode="AU" term="%22Anguita+E%22">Anguita E</searchLink>; Hematology Department, Hospital Clínico San Carlos (HCSC), IML, IdISSC, Department of Medicine Universidad Complutense de Madrid (UCM) Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Naimo+A%22">Naimo A</searchLink>; Gustave Roussy, Genomic Platform Université Paris-Saclay, UMS AMMICA, INSERM US23, CNRS UMS 3655 Villejuif France.<br /><searchLink fieldCode="AU" term="%22Marzac+C%22">Marzac C</searchLink>; Department of Hematology Leukemia Interception Program, Personalized Cancer Prevention Center, Gustave Roussy Villejuif France.<br /><searchLink fieldCode="AU" term="%22Pflumio+F%22">Pflumio F</searchLink>; Equipe Labellisée Ligue Contre le Cancer Paris France.; Unité de Recherche (UMR)-E008 Stabilité Génétique, Cellules Souches et Radiations, Team Niche and Cancer in Hematopoiesis, Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA) Université de Paris-Université Paris-Saclay Fontenay-aux-Roses France.; OPALE Carnot Institute, The Organization for Partnerships in Leukemia Paris France.<br /><searchLink fieldCode="AU" term="%22Malinge+S%22">Malinge S</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Telethon Kids Institute, Perth Children's Hospital Nedlands Australia.<br /><searchLink fieldCode="AU" term="%22Wichmann+C%22">Wichmann C</searchLink>; Department of Transfusion Medicine, Cell Therapeutics and Haemostasis Ludwig-Maximilians-University of Munich Munich Germany.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland.<br /><searchLink fieldCode="AU" term="%22Lobry+C%22">Lobry C</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; INSERM U944, CNRS UMR7212 Institut de Recherche Saint Louis and Université de Paris Paris France.<br /><searchLink fieldCode="AU" term="%22Chaumeil+J%22">Chaumeil J</searchLink>; Université de Paris, Institut Cochin, INSERM, CNRS Paris France.<br /><searchLink fieldCode="AU" term="%22Soler+E%22">Soler E</searchLink>; IGMM, University of Montpellier, CNRS, Montpellier, France & Université de Paris, Laboratory of Excellence GR-Ex Paris France.<br /><searchLink fieldCode="AU" term="%22Bourquin+JP%22">Bourquin JP</searchLink>; Division of Oncology and Children's Research Centre University Children's Hospital Zurich Zurich Switzerland.<br /><searchLink fieldCode="AU" term="%22Nerlov+C%22">Nerlov C</searchLink>; MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital University of Oxford Oxford UK.<br /><searchLink fieldCode="AU" term="%22Bernard+OA%22">Bernard OA</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.<br /><searchLink fieldCode="AU" term="%22Schwaller+J%22">Schwaller J</searchLink>; Department of Biomedicine University Children's Hospital Beider Basel (UKBB), University of Basel Basel Switzerland.<br /><searchLink fieldCode="AU" term="%22Mercher+T%22">Mercher T</searchLink>; Gustave Roussy, INSERM U1170 Université Paris-Saclay Villejuif France.; Equipe Labellisée Ligue Contre le Cancer Paris France.; OPALE Carnot Institute, The Organization for Partnerships in Leukemia Paris France.
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