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Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes.

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Title: Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes.
Authors: Atreya MR; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA. Mihir.Atreya@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA. Mihir.Atreya@cchmc.org., Huang M; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Moore AR; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA., Zheng H; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Hasin-Brumshtein Y; Inflammatix, Sunnyvale, CA, 94085, USA., Fitzgerald JC; Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Weiss SL; Nemours Children's Health, Wilmington, DE, 19803, USA., Cvijanovich NZ; UCSF Benioff Children's Hospital Oakland, Oakland, CA, 94609, USA., Bigham MT; Akron Children's Hospital, Akron, OH, 44308, USA., Jain PN; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA., Schwarz AJ; Children's Hospital of Orange County, Orange, CA, 92868, USA., Lutfi R; Riley Hospital for Children, Indianapolis, IN, 46202, USA., Nowak J; Children's Hospital and Clinics of Minnesota, Minneapolis, MN, 55404, USA., Thomas NJ; Penn State Hershey Children's Hospital, Hershey, PA, 17033, USA., Quasney M; C.S Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 48109, USA., Dahmer MK; C.S Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 48109, USA., Baines T; University of Florida Health Children's Hospital, Gainesville, FL, 32610, USA., Haileselassie B; Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 94304, USA., Lautz AJ; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA., Stanski NL; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA., Standage SW; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA., Kaplan JM; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA., Zingarelli B; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA., Sahay R; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Zhang B; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA., Sweeney TE; Inflammatix, Sunnyvale, CA, 94085, USA., Khatri P; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Sanchez-Pinto LN; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Health and Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Kamaleswaran R; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 30322, USA.
Source: Critical care (London, England) [Crit Care] 2024 Jul 17; Vol. 28 (1), pp. 246. Date of Electronic Publication: 2024 Jul 17.
Publication Type: Journal Article; Observational Study; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes.
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  Data: <searchLink fieldCode="AU" term="%22Atreya+MR%22">Atreya MR</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA. Mihir.Atreya@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA. Mihir.Atreya@cchmc.org.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Moore+AR%22">Moore AR</searchLink>; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Hasin-Brumshtein+Y%22">Hasin-Brumshtein Y</searchLink>; Inflammatix, Sunnyvale, CA, 94085, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+JC%22">Fitzgerald JC</searchLink>; Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+SL%22">Weiss SL</searchLink>; Nemours Children's Health, Wilmington, DE, 19803, USA.<br /><searchLink fieldCode="AU" term="%22Cvijanovich+NZ%22">Cvijanovich NZ</searchLink>; UCSF Benioff Children's Hospital Oakland, Oakland, CA, 94609, USA.<br /><searchLink fieldCode="AU" term="%22Bigham+MT%22">Bigham MT</searchLink>; Akron Children's Hospital, Akron, OH, 44308, USA.<br /><searchLink fieldCode="AU" term="%22Jain+PN%22">Jain PN</searchLink>; Texas Children's Hospital, Baylor College of Medicine, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Schwarz+AJ%22">Schwarz AJ</searchLink>; Children's Hospital of Orange County, Orange, CA, 92868, USA.<br /><searchLink fieldCode="AU" term="%22Lutfi+R%22">Lutfi R</searchLink>; Riley Hospital for Children, Indianapolis, IN, 46202, USA.<br /><searchLink fieldCode="AU" term="%22Nowak+J%22">Nowak J</searchLink>; Children's Hospital and Clinics of Minnesota, Minneapolis, MN, 55404, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+NJ%22">Thomas NJ</searchLink>; Penn State Hershey Children's Hospital, Hershey, PA, 17033, USA.<br /><searchLink fieldCode="AU" term="%22Quasney+M%22">Quasney M</searchLink>; C.S Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Dahmer+MK%22">Dahmer MK</searchLink>; C.S Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Baines+T%22">Baines T</searchLink>; University of Florida Health Children's Hospital, Gainesville, FL, 32610, USA.<br /><searchLink fieldCode="AU" term="%22Haileselassie+B%22">Haileselassie B</searchLink>; Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 94304, USA.<br /><searchLink fieldCode="AU" term="%22Lautz+AJ%22">Lautz AJ</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA.<br /><searchLink fieldCode="AU" term="%22Stanski+NL%22">Stanski NL</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA.<br /><searchLink fieldCode="AU" term="%22Standage+SW%22">Standage SW</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA.<br /><searchLink fieldCode="AU" term="%22Kaplan+JM%22">Kaplan JM</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA.<br /><searchLink fieldCode="AU" term="%22Zingarelli+B%22">Zingarelli B</searchLink>; Division of Critical Care Medicine, MLC2005, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45627, USA.<br /><searchLink fieldCode="AU" term="%22Sahay+R%22">Sahay R</searchLink>; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.<br /><searchLink fieldCode="AU" term="%22Sweeney+TE%22">Sweeney TE</searchLink>; Inflammatix, Sunnyvale, CA, 94085, USA.<br /><searchLink fieldCode="AU" term="%22Khatri+P%22">Khatri P</searchLink>; Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA.; Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez-Pinto+LN%22">Sanchez-Pinto LN</searchLink>; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Department of Health and Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Kamaleswaran+R%22">Kamaleswaran R</searchLink>; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, 30322, USA.
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  Data: <searchLink fieldCode="JN" term="%229801902%22">Critical care (London, England)</searchLink> [Crit Care] 2024 Jul 17; Vol. 28 (1), pp. 246. <i>Date of Electronic Publication: </i>2024 Jul 17.
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