Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites.
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| Title: | Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites. |
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| Authors: | Trotta AM; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Tomassi S; Department of Pharmacy, University of Naples 'Federico II', 80131, Naples, Italy., Di Maiolo G; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Ieranò C; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Vetrei C; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., D'Alterio C; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Merlino F; Department of Pharmacy, University of Naples 'Federico II', 80131, Naples, Italy., Messere A; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., D'Aniello A; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Del Bene A; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Mazzarella V; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Roggia M; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Natale B; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Cutolo R; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Campagna E; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Mottola S; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Russo R; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Chambery A; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy., Benedetti R; Department of Precision Medicine, University of Campania ''Luigi Vanvitelli'', Vico L. De Crecchio 7, 80138, Naples, Italy; Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy., Altucci L; Department of Precision Medicine, University of Campania ''Luigi Vanvitelli'', Vico L. De Crecchio 7, 80138, Naples, Italy; Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy; Institute of Endocrinology and Oncology 'Gaetano Salvatore' (IEOS), 80131, Naples, Italy; Biogem Institute of Molecular and Genetic Biology, 83031, Ariano Irpino, Italy., Cosconati S; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy. Electronic address: sandro.cosconati@unicampania.it., Scala S; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy. Electronic address: scalaste@gmail.com., Di Maro S; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy. Electronic address: salvatore.dimaro@unicampania.it. |
| Source: | European journal of medicinal chemistry [Eur J Med Chem] 2024 Oct 05; Vol. 276, pp. 116669. Date of Electronic Publication: 2024 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39053189 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Trotta+AM%22">Trotta AM</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Tomassi+S%22">Tomassi S</searchLink>; Department of Pharmacy, University of Naples 'Federico II', 80131, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Maiolo+G%22">Di Maiolo G</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Ieranò+C%22">Ieranò C</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Vetrei+C%22">Vetrei C</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22D'Alterio+C%22">D'Alterio C</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Merlino+F%22">Merlino F</searchLink>; Department of Pharmacy, University of Naples 'Federico II', 80131, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Messere+A%22">Messere A</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22D'Aniello+A%22">D'Aniello A</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Bene+A%22">Del Bene A</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzarella+V%22">Mazzarella V</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Roggia+M%22">Roggia M</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Natale+B%22">Natale B</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Cutolo+R%22">Cutolo R</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Campagna+E%22">Campagna E</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Mottola+S%22">Mottola S</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Russo+R%22">Russo R</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Chambery+A%22">Chambery A</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Benedetti+R%22">Benedetti R</searchLink>; Department of Precision Medicine, University of Campania ''Luigi Vanvitelli'', Vico L. De Crecchio 7, 80138, Naples, Italy; Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Altucci+L%22">Altucci L</searchLink>; Department of Precision Medicine, University of Campania ''Luigi Vanvitelli'', Vico L. De Crecchio 7, 80138, Naples, Italy; Program of Medical Epigenetics, Vanvitelli Hospital, Naples, Italy; Institute of Endocrinology and Oncology 'Gaetano Salvatore' (IEOS), 80131, Naples, Italy; Biogem Institute of Molecular and Genetic Biology, 83031, Ariano Irpino, Italy.<br /><searchLink fieldCode="AU" term="%22Cosconati+S%22">Cosconati S</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy. Electronic address: sandro.cosconati@unicampania.it.<br /><searchLink fieldCode="AU" term="%22Scala+S%22">Scala S</searchLink>; Microenvironment Molecular Targets, Istituto Nazionale Tumori-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy. Electronic address: scalaste@gmail.com.<br /><searchLink fieldCode="AU" term="%22Di+Maro+S%22">Di Maro S</searchLink>; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania 'Luigi Vanvitelli', 81100, Caserta, Italy. Electronic address: salvatore.dimaro@unicampania.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2024 Oct 05; Vol. 276, pp. 116669. <i>Date of Electronic Publication: </i>2024 Jul 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejmech.2024.116669 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 116669 Titles: – TitleFull: Disulfide bond replacement with non-reducible side chain to tail macrolactamization for the development of potent and selective CXCR4 peptide antagonists endowed with flanking binding sites. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Trotta AM – PersonEntity: Name: NameFull: Tomassi S – PersonEntity: Name: NameFull: Di Maiolo G – PersonEntity: Name: NameFull: Ieranò C – PersonEntity: Name: NameFull: Vetrei C – PersonEntity: Name: NameFull: D'Alterio C – PersonEntity: Name: NameFull: Merlino F – PersonEntity: Name: NameFull: Messere A – PersonEntity: Name: NameFull: D'Aniello A – PersonEntity: Name: NameFull: Del Bene A – PersonEntity: Name: NameFull: Mazzarella V – PersonEntity: Name: NameFull: Roggia M – PersonEntity: Name: NameFull: Natale B – PersonEntity: Name: NameFull: Cutolo R – PersonEntity: Name: NameFull: Campagna E – PersonEntity: Name: NameFull: Mottola S – PersonEntity: Name: NameFull: Russo R – PersonEntity: Name: NameFull: Chambery A – PersonEntity: Name: NameFull: Benedetti R – PersonEntity: Name: NameFull: Altucci L – PersonEntity: Name: NameFull: Cosconati S – PersonEntity: Name: NameFull: Scala S – PersonEntity: Name: NameFull: Di Maro S IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 10 Text: 2024 Oct 05 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1768-3254 Numbering: – Type: volume Value: 276 Titles: – TitleFull: European journal of medicinal chemistry Type: main |
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