Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate-to-severe atopic dermatitis: Results from two terminated phase II trials.

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Title: Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate-to-severe atopic dermatitis: Results from two terminated phase II trials.
Authors: Kosloski MP; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Guttman-Yassky E; Icahn School of Medicine at Mount Sinai Medical Center, New York, New York, USA.; Rockefeller University, New York, New York, USA., Cork MJ; Sheffield Dermatology Research, University of Sheffield, Sheffield, UK.; Sheffield Children's Hospital, Sheffield, UK., Worm M; Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany., Nahm DH; Ajou University Hospital, Suwon, Korea., Zhu X; Formerly Regeneron Pharmaceuticals Inc., Basking Ridge, New Jersy, USA., Ruddy MK; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Harel S; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Kamal MA; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Goulaouic H; Sanofi, Chilly-Mazarin, France., Xu CR; Sanofi, Bridgewater, New Jersey, USA., Avetisova E; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Davis JD; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA., Nivens MC; Formerly Regeneron Pharmaceuticals, Tarrytown, New York, USA., Shabbir A; Formerly Regeneron Pharmaceuticals, Tarrytown, New York, USA., Radin A; Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA.
Source: Clinical and translational science [Clin Transl Sci] 2024 Aug; Vol. 17 (8), pp. e13874.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1752-8062
DOI:10.1111/cts.13874