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Incidence, Risk Factors, and Long-Term Outcomes for Extubation Failure in ICU in Patients With Obesity: A Retrospective Analysis of a Multicenter Prospective Observational Study.

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Title: Incidence, Risk Factors, and Long-Term Outcomes for Extubation Failure in ICU in Patients With Obesity: A Retrospective Analysis of a Multicenter Prospective Observational Study.
Authors: De Jong A; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Capdevila M; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Aarab Y; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Cros M; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Pensier J; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Lakbar I; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Monet C; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Quintard H; Division of Intensive Care, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Cinotti R; Intensive Care and Anesthesiology Department, University of Nantes, Hotel-Dieu Hospital, Nantes, France., Asehnoune K; Intensive Care and Anesthesiology Department, University of Nantes, Hotel-Dieu Hospital, Nantes, France., Arnal JM; Intensive Care Department, Sainte Musse Hospital, Toulon, France., Guitton C; Medical ICU, Hôtel-Dieu Teaching Hospital, Nantes, France., Paugam-Burtz C; Intensive Care and Anesthesiology Department, Paris Diderot University, Sorbonne Paris Cité, and AP-HP, Hôpital Beaujon, Paris, France., Abback P; Intensive Care and Anesthesiology Department, Paris Diderot University, Sorbonne Paris Cité, and AP-HP, Hôpital Beaujon, Paris, France., Mekontso-Dessap A; Service de Réanimation Médicale, DHU A-TVB, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Groupe de Recherche Clinique CARMAS, Faculté de Médecine de Créteil, Université Paris Est Créteil, Créteil, France., Lakhal K; Intensive Care and Anesthesiology Department, University of Nantes, Laennec Nord Hospital, Nantes, France., Lasocki S; Département Anesthésie Réanimation, CHU Angers, Angers, France., Plantefeve G; Medical-Surgical ICU, General Hospital Center, Argenteuil, France., Claud B; Medical-Surgical ICU, General Hospital Center, Le Puy-en-Velay, France., Pottecher J; Hôpitaux Universitaires de Strasbourg, Pôle Anesthésie Réanimation Chirurgicale SAMU, Hôpital de Hautepierre, Service d'Anesthésie-Réanimation Chirurgicale, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Institut de Physiologie, Equipe d'Accueil EA3072 'Mitochondrie, Stress Oxydant et Protection Musculaire,' Strasbourg, France., Corne P; Medical ICU, Montpellier University Hospital, Montpellier, France., Ichai C; Division of Intensive Care, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Molinari N; IDESP, INSERM, PreMEdical INRIA, University Montpellier, CHU Montpellier, Montpellier, France., Chanques G; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France., Papazian L; APHM, URMITE UMR CNRS 7278, Hôpital Nord, Réanimation des Détresses Respiratoires et Infections Sévères, Aix-Marseille University, Marseille, France., Azoulay E; Medical ICU, University of Paris-Diderot, Saint Louis Hospital, Paris, France., Jaber S; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France. Electronic address: s-jaber@chu-montpellier.fr.
Corporate Authors: FREE-REA Study Group
Source: Chest [Chest] 2025 Jan; Vol. 167 (1), pp. 139-151. Date of Electronic Publication: 2024 Sep 07.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0231335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1931-3543 (Electronic) Linking ISSN: 00123692 NLM ISO Abbreviation: Chest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Incidence, Risk Factors, and Long-Term Outcomes for Extubation Failure in ICU in Patients With Obesity: A Retrospective Analysis of a Multicenter Prospective Observational Study.
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  Data: <searchLink fieldCode="AU" term="%22De+Jong+A%22">De Jong A</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Capdevila+M%22">Capdevila M</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Aarab+Y%22">Aarab Y</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Cros+M%22">Cros M</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Pensier+J%22">Pensier J</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Lakbar+I%22">Lakbar I</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Monet+C%22">Monet C</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Quintard+H%22">Quintard H</searchLink>; Division of Intensive Care, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cinotti+R%22">Cinotti R</searchLink>; Intensive Care and Anesthesiology Department, University of Nantes, Hotel-Dieu Hospital, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Asehnoune+K%22">Asehnoune K</searchLink>; Intensive Care and Anesthesiology Department, University of Nantes, Hotel-Dieu Hospital, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Arnal+JM%22">Arnal JM</searchLink>; Intensive Care Department, Sainte Musse Hospital, Toulon, France.<br /><searchLink fieldCode="AU" term="%22Guitton+C%22">Guitton C</searchLink>; Medical ICU, Hôtel-Dieu Teaching Hospital, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Paugam-Burtz+C%22">Paugam-Burtz C</searchLink>; Intensive Care and Anesthesiology Department, Paris Diderot University, Sorbonne Paris Cité, and AP-HP, Hôpital Beaujon, Paris, France.<br /><searchLink fieldCode="AU" term="%22Abback+P%22">Abback P</searchLink>; Intensive Care and Anesthesiology Department, Paris Diderot University, Sorbonne Paris Cité, and AP-HP, Hôpital Beaujon, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mekontso-Dessap+A%22">Mekontso-Dessap A</searchLink>; Service de Réanimation Médicale, DHU A-TVB, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Groupe de Recherche Clinique CARMAS, Faculté de Médecine de Créteil, Université Paris Est Créteil, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Lakhal+K%22">Lakhal K</searchLink>; Intensive Care and Anesthesiology Department, University of Nantes, Laennec Nord Hospital, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Lasocki+S%22">Lasocki S</searchLink>; Département Anesthésie Réanimation, CHU Angers, Angers, France.<br /><searchLink fieldCode="AU" term="%22Plantefeve+G%22">Plantefeve G</searchLink>; Medical-Surgical ICU, General Hospital Center, Argenteuil, France.<br /><searchLink fieldCode="AU" term="%22Claud+B%22">Claud B</searchLink>; Medical-Surgical ICU, General Hospital Center, Le Puy-en-Velay, France.<br /><searchLink fieldCode="AU" term="%22Pottecher+J%22">Pottecher J</searchLink>; Hôpitaux Universitaires de Strasbourg, Pôle Anesthésie Réanimation Chirurgicale SAMU, Hôpital de Hautepierre, Service d'Anesthésie-Réanimation Chirurgicale, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Institut de Physiologie, Equipe d'Accueil EA3072 'Mitochondrie, Stress Oxydant et Protection Musculaire,' Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Corne+P%22">Corne P</searchLink>; Medical ICU, Montpellier University Hospital, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Ichai+C%22">Ichai C</searchLink>; Division of Intensive Care, Geneva University Hospitals, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Molinari+N%22">Molinari N</searchLink>; IDESP, INSERM, PreMEdical INRIA, University Montpellier, CHU Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Chanques+G%22">Chanques G</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Papazian+L%22">Papazian L</searchLink>; APHM, URMITE UMR CNRS 7278, Hôpital Nord, Réanimation des Détresses Respiratoires et Infections Sévères, Aix-Marseille University, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Azoulay+E%22">Azoulay E</searchLink>; Medical ICU, University of Paris-Diderot, Saint Louis Hospital, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jaber+S%22">Jaber S</searchLink>; Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, and Centre Hospitalier Universitaire Montpellier, Montpellier, France. 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