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Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.

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Title: Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.
Authors: Ney A; Institute for Liver and Digestive Health, University College London, London, United Kingdom., Nené NR; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; Cancer Institute, University College London, London, United Kingdom.; Department of Statistical Science, University College London, London, United Kingdom., Sedlak E; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom., Acedo P; Institute for Liver and Digestive Health, University College London, London, United Kingdom., Blyuss O; Center for Cancer Prevention, Detection and Early Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom.; Department of Pediatrics and Pediatric Infectious Diseases, Institute of Child´s Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Whitwell HJ; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; National Phenome Centre and Imperial Clinical Phenotyping Centre, Department of Metabolism, Digestion and Reproduction, IRDB, Building Imperial College London, London, United Kingdom.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom., Costello E; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom., Gentry-Maharaj A; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, United Kingdom., Williams NR; Division of Surgery & Interventional Science, University College London, London, United Kingdom., Menon U; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, United Kingdom., Fusai GK; HPB & Liver Transplant Unit, Royal Free London, London, United Kingdom., Zaikin A; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; Institute for Cognitive Neuroscience, University Higher School of Economics, Moscow, Russia.; Department of Mathematics, University College London, London, United Kingdom.; Centre for Cognition and Decision making, Institute for Cognitive Neuroscience, HSE University, Moscow, Russia.; Life Improvement by Future Technologies (LIFT) Center, Skolkovo, Moscow, Russia., Pereira SP; Institute for Liver and Digestive Health, University College London, London, United Kingdom.
Source: PLoS computational biology [PLoS Comput Biol] 2024 Aug 29; Vol. 20 (8), pp. e1012408. Date of Electronic Publication: 2024 Aug 29 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ney+A%22">Ney A</searchLink>; Institute for Liver and Digestive Health, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nené+NR%22">Nené NR</searchLink>; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; Cancer Institute, University College London, London, United Kingdom.; Department of Statistical Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sedlak+E%22">Sedlak E</searchLink>; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Acedo+P%22">Acedo P</searchLink>; Institute for Liver and Digestive Health, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Blyuss+O%22">Blyuss O</searchLink>; Center for Cancer Prevention, Detection and Early Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom.; Department of Pediatrics and Pediatric Infectious Diseases, Institute of Child´s Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Whitwell+HJ%22">Whitwell HJ</searchLink>; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; National Phenome Centre and Imperial Clinical Phenotyping Centre, Department of Metabolism, Digestion and Reproduction, IRDB, Building Imperial College London, London, United Kingdom.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Costello+E%22">Costello E</searchLink>; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gentry-Maharaj+A%22">Gentry-Maharaj A</searchLink>; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Williams+NR%22">Williams NR</searchLink>; Division of Surgery & Interventional Science, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Menon+U%22">Menon U</searchLink>; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fusai+GK%22">Fusai GK</searchLink>; HPB & Liver Transplant Unit, Royal Free London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zaikin+A%22">Zaikin A</searchLink>; Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.; Institute for Cognitive Neuroscience, University Higher School of Economics, Moscow, Russia.; Department of Mathematics, University College London, London, United Kingdom.; Centre for Cognition and Decision making, Institute for Cognitive Neuroscience, HSE University, Moscow, Russia.; Life Improvement by Future Technologies (LIFT) Center, Skolkovo, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Pereira+SP%22">Pereira SP</searchLink>; Institute for Liver and Digestive Health, University College London, London, United Kingdom.
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