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A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors.

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Title: A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors.
Authors: Brands J; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany., Bravo S; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Jürgenliemke L; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 2873, University of Bonn, Bonn, Germany., Grätz L; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Schihada H; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany., Frechen F; Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany., Alenfelder J; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Pfeil C; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany.; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Ohse PG; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Hiratsuka S; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan., Kawakami K; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.; Komaba Institute for Science, The University of Tokyo, Meguro, Tokyo, 153-8505, Japan., Schmacke LC; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany., Heycke N; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan., König G; Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Pfeifer A; Institute of Pharmacology and Toxicology, University Hospital, University of Bonn, Bonn, Germany., Wachten D; Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany., Schulte G; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Steinmetzer T; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany., Watts VJ; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute of Drug Discovery, Purdue University, West Lafayette, IN, USA., Gomeza J; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany., Simon K; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131, Padova, Italy., Kostenis E; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany. kostenis@uni-bonn.de.
Source: Nature communications [Nat Commun] 2024 Sep 03; Vol. 15 (1), pp. 7684. Date of Electronic Publication: 2024 Sep 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A molecular mechanism to diversify Ca<superscript>2+</superscript> signaling downstream of Gs protein-coupled receptors.
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  Data: <searchLink fieldCode="AU" term="%22Brands+J%22">Brands J</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bravo+S%22">Bravo S</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Jürgenliemke+L%22">Jürgenliemke L</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 2873, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Grätz+L%22">Grätz L</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Schihada+H%22">Schihada H</searchLink>; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Frechen+F%22">Frechen F</searchLink>; Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Alenfelder+J%22">Alenfelder J</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Pfeil+C%22">Pfeil C</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Research Training Group 1873, University of Bonn, Bonn, Germany.; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Ohse+PG%22">Ohse PG</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hiratsuka+S%22">Hiratsuka S</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.<br /><searchLink fieldCode="AU" term="%22Kawakami+K%22">Kawakami K</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.; Komaba Institute for Science, The University of Tokyo, Meguro, Tokyo, 153-8505, Japan.<br /><searchLink fieldCode="AU" term="%22Schmacke+LC%22">Schmacke LC</searchLink>; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Heycke+N%22">Heycke N</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Inoue+A%22">Inoue A</searchLink>; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan.; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan.<br /><searchLink fieldCode="AU" term="%22König+G%22">König G</searchLink>; Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Pfeifer+A%22">Pfeifer A</searchLink>; Institute of Pharmacology and Toxicology, University Hospital, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wachten+D%22">Wachten D</searchLink>; Institute of Innate Immunity, Medical Faculty, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schulte+G%22">Schulte G</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Steinmetzer+T%22">Steinmetzer T</searchLink>; Department of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Watts+VJ%22">Watts VJ</searchLink>; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute of Drug Discovery, Purdue University, West Lafayette, IN, USA.<br /><searchLink fieldCode="AU" term="%22Gomeza+J%22">Gomeza J</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+K%22">Simon K</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany.; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Kostenis+E%22">Kostenis E</searchLink>; Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany. kostenis@uni-bonn.de.
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