Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide.
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| Title: | Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide. |
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| Authors: | El Fakiri M; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Regupathy AR; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Uhlmann L; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Ayada N; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Geis NM; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Domogalla LC; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Lahdenranta J; Bicycle Therapeutics, 35 Cambridgepark Drive, Cambridge, MA, 02140, United States., Blakeman B; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Wood F; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Meyer PT; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany., Huxley P; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Eder M; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany., Mudd GE; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom., Eder AC; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. |
| Source: | Theranostics [Theranostics] 2024 Aug 06; Vol. 14 (12), pp. 4701-4712. Date of Electronic Publication: 2024 Aug 06 (Print Publication: 2024). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39239524 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22El+Fakiri+M%22">El Fakiri M</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Regupathy+AR%22">Regupathy AR</searchLink>; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Uhlmann+L%22">Uhlmann L</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ayada+N%22">Ayada N</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Geis+NM%22">Geis NM</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Domogalla+LC%22">Domogalla LC</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lahdenranta+J%22">Lahdenranta J</searchLink>; Bicycle Therapeutics, 35 Cambridgepark Drive, Cambridge, MA, 02140, United States.<br /><searchLink fieldCode="AU" term="%22Blakeman+B%22">Blakeman B</searchLink>; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wood+F%22">Wood F</searchLink>; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Meyer+PT%22">Meyer PT</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Huxley+P%22">Huxley P</searchLink>; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Eder+M%22">Eder M</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Mudd+GE%22">Mudd GE</searchLink>; BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Eder+AC%22">Eder AC</searchLink>; Department of Nuclear Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), partner site Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany and German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2024 Aug 06; Vol. 14 (12), pp. 4701-4712. <i>Date of Electronic Publication: </i>2024 Aug 06 (<i>Print Publication: </i>2024). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39239524 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7150/thno.96641 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 4701 Titles: – TitleFull: Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: El Fakiri M – PersonEntity: Name: NameFull: Regupathy AR – PersonEntity: Name: NameFull: Uhlmann L – PersonEntity: Name: NameFull: Ayada N – PersonEntity: Name: NameFull: Geis NM – PersonEntity: Name: NameFull: Domogalla LC – PersonEntity: Name: NameFull: Lahdenranta J – PersonEntity: Name: NameFull: Blakeman B – PersonEntity: Name: NameFull: Wood F – PersonEntity: Name: NameFull: Meyer PT – PersonEntity: Name: NameFull: Huxley P – PersonEntity: Name: NameFull: Eder M – PersonEntity: Name: NameFull: Mudd GE – PersonEntity: Name: NameFull: Eder AC IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 08 Text: 2024 Aug 06 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1838-7640 Numbering: – Type: volume Value: 14 – Type: issue Value: 12 Titles: – TitleFull: Theranostics Type: main |
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