View in EDS HTML Full Text PDF Full Text

Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.

Saved in:
Bibliographic Details
Title: Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.
Authors: Sangana R; PK Sciences, Biomedical Research, Novartis, Cambridge, MA, USA., Ogutu B; Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya and CREATES, Strathmore University, Nairobi, Kenya., Yeka A; Infectious Diseases Research Collaboration, Kampala, Uganda., Kusemererwa S; Medical Research Council/Uganda Virus Resea, rch Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Tinto H; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso., Toure AO; Department of Parasitology-Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire., Kibuuka A; Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda., Lingani M; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso., Lourenço C; Chókwè Health Research and Training Center/Centro de Investigação e Treino em Saúde de Chókwè (CITSC), National Institute of Health, Mozambique., Mombo-Ngoma G; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine and Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Nduba V; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya., Landry N'Guessan T; Department of Parasitology-Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire., Nassa GJW; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso., Nyantaro M; Medical Research Council/Uganda Virus Resea, rch Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda., Tina LO; Centre for Clinical Research, Kenya Medical Research Institute/US Army Medical Research Directorate, Kisumu, Kenya., Anvikar A; ICMR-National Institute of Malaria Research, New Delhi, India., Sinha A; ICMR-National Institute of Malaria Research, New Delhi, India., Kaguthi G; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya., Fofana B; Malaria Research and Training Center, Bamako, Mali., Grobusch MP; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany., Gaaloul ME; Medicines for Malaria Venture, Geneva, Switzerland., Marrast AC; Medicines for Malaria Venture, Geneva, Switzerland., Pathan R; Novartis Healthcare Pvt. Ltd., Hyderabad, India., Chikoto H; Novartis Healthcare Pvt. Ltd., Hyderabad, India., Csermak K; Novartis Healthcare Pvt. Ltd., Hyderabad, India., Risterucci C; Novartis Healthcare Pvt. Ltd., Hyderabad, India., Su G; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Winnips C; Novartis Pharma AG, Basel, Switzerland., Zhang J; PK Sciences, Biomedical Research, Novartis, East Hanover, NJ, USA., Zack J; PK Sciences, Biomedical Research, Novartis, East Hanover, NJ, USA.
Source: Journal of clinical pharmacology [J Clin Pharmacol] 2025 Feb; Vol. 65 (2), pp. 179-189. Date of Electronic Publication: 2024 Sep 29.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39344281
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Sangana+R%22">Sangana R</searchLink>; PK Sciences, Biomedical Research, Novartis, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ogutu+B%22">Ogutu B</searchLink>; Centre for Clinical Research, Kenya Medical Research Institute, Kisumu, Kenya and CREATES, Strathmore University, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Yeka+A%22">Yeka A</searchLink>; Infectious Diseases Research Collaboration, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kusemererwa+S%22">Kusemererwa S</searchLink>; Medical Research Council/Uganda Virus Resea, rch Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Tinto+H%22">Tinto H</searchLink>; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso.<br /><searchLink fieldCode="AU" term="%22Toure+AO%22">Toure AO</searchLink>; Department of Parasitology-Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire.<br /><searchLink fieldCode="AU" term="%22Kibuuka+A%22">Kibuuka A</searchLink>; Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Lingani+M%22">Lingani M</searchLink>; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso.<br /><searchLink fieldCode="AU" term="%22Lourenço+C%22">Lourenço C</searchLink>; Chókwè Health Research and Training Center/Centro de Investigação e Treino em Saúde de Chókwè (CITSC), National Institute of Health, Mozambique.<br /><searchLink fieldCode="AU" term="%22Mombo-Ngoma+G%22">Mombo-Ngoma G</searchLink>; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine and Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Nduba+V%22">Nduba V</searchLink>; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Landry+N'Guessan+T%22">Landry N'Guessan T</searchLink>; Department of Parasitology-Mycology, Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire.<br /><searchLink fieldCode="AU" term="%22Nassa+GJW%22">Nassa GJW</searchLink>; Institut de Recherche en Science de la Santé - Unité de Recherche Clinique de Nanoro (IRSS-URCN), Nanoro, Burkina Faso.<br /><searchLink fieldCode="AU" term="%22Nyantaro+M%22">Nyantaro M</searchLink>; Medical Research Council/Uganda Virus Resea, rch Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Tina+LO%22">Tina LO</searchLink>; Centre for Clinical Research, Kenya Medical Research Institute/US Army Medical Research Directorate, Kisumu, Kenya.<br /><searchLink fieldCode="AU" term="%22Anvikar+A%22">Anvikar A</searchLink>; ICMR-National Institute of Malaria Research, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Sinha+A%22">Sinha A</searchLink>; ICMR-National Institute of Malaria Research, New Delhi, India.<br /><searchLink fieldCode="AU" term="%22Kaguthi+G%22">Kaguthi G</searchLink>; Kenya Medical Research Institute-Centre for Respiratory Diseases Research (KEMRI-CRDR), Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Fofana+B%22">Fofana B</searchLink>; Malaria Research and Training Center, Bamako, Mali.<br /><searchLink fieldCode="AU" term="%22Grobusch+MP%22">Grobusch MP</searchLink>; Centre de Recherches Médicales de Lambaréné (CERMEL), Lambaréné, Gabon.; Department of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gaaloul+ME%22">Gaaloul ME</searchLink>; Medicines for Malaria Venture, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marrast+AC%22">Marrast AC</searchLink>; Medicines for Malaria Venture, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pathan+R%22">Pathan R</searchLink>; Novartis Healthcare Pvt. Ltd., Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Chikoto+H%22">Chikoto H</searchLink>; Novartis Healthcare Pvt. Ltd., Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Csermak+K%22">Csermak K</searchLink>; Novartis Healthcare Pvt. Ltd., Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Risterucci+C%22">Risterucci C</searchLink>; Novartis Healthcare Pvt. Ltd., Hyderabad, India.<br /><searchLink fieldCode="AU" term="%22Su+G%22">Su G</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Winnips+C%22">Winnips C</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; PK Sciences, Biomedical Research, Novartis, East Hanover, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Zack+J%22">Zack J</searchLink>; PK Sciences, Biomedical Research, Novartis, East Hanover, NJ, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220366372%22">Journal of clinical pharmacology</searchLink> [J Clin Pharmacol] 2025 Feb; Vol. 65 (2), pp. 179-189. <i>Date of Electronic Publication: </i>2024 Sep 29.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0366372 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-4604 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200912700%22">00912700 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Pharmacol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39344281
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/jcph.6138
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 179
    Titles:
      – TitleFull: Pharmacokinetics of Ganaplacide and Lumefantrine in Adults, Adolescents, and Children with Plasmodium falciparum Malaria Treated with Ganaplacide Plus Lumefantrine Solid Dispersion Formulation: Analysis of Data from a Multinational Phase 2 Study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sangana R
      – PersonEntity:
          Name:
            NameFull: Ogutu B
      – PersonEntity:
          Name:
            NameFull: Yeka A
      – PersonEntity:
          Name:
            NameFull: Kusemererwa S
      – PersonEntity:
          Name:
            NameFull: Tinto H
      – PersonEntity:
          Name:
            NameFull: Toure AO
      – PersonEntity:
          Name:
            NameFull: Kibuuka A
      – PersonEntity:
          Name:
            NameFull: Lingani M
      – PersonEntity:
          Name:
            NameFull: Lourenço C
      – PersonEntity:
          Name:
            NameFull: Mombo-Ngoma G
      – PersonEntity:
          Name:
            NameFull: Nduba V
      – PersonEntity:
          Name:
            NameFull: Landry N'Guessan T
      – PersonEntity:
          Name:
            NameFull: Nassa GJW
      – PersonEntity:
          Name:
            NameFull: Nyantaro M
      – PersonEntity:
          Name:
            NameFull: Tina LO
      – PersonEntity:
          Name:
            NameFull: Anvikar A
      – PersonEntity:
          Name:
            NameFull: Sinha A
      – PersonEntity:
          Name:
            NameFull: Kaguthi G
      – PersonEntity:
          Name:
            NameFull: Fofana B
      – PersonEntity:
          Name:
            NameFull: Grobusch MP
      – PersonEntity:
          Name:
            NameFull: Gaaloul ME
      – PersonEntity:
          Name:
            NameFull: Marrast AC
      – PersonEntity:
          Name:
            NameFull: Pathan R
      – PersonEntity:
          Name:
            NameFull: Chikoto H
      – PersonEntity:
          Name:
            NameFull: Csermak K
      – PersonEntity:
          Name:
            NameFull: Risterucci C
      – PersonEntity:
          Name:
            NameFull: Su G
      – PersonEntity:
          Name:
            NameFull: Winnips C
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Zack J
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2025 Feb
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1552-4604
          Numbering:
            – Type: volume
              Value: 65
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Journal of clinical pharmacology
              Type: main
ResultId 1