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Clinical Reasoning: Assessing New Neurologic Deficits in Patients With Hematologic Malignancy on Bruton Tyrosine Kinase Inhibitor Therapy.

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Title: Clinical Reasoning: Assessing New Neurologic Deficits in Patients With Hematologic Malignancy on Bruton Tyrosine Kinase Inhibitor Therapy.
Authors: Nelson TA; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Murthy NK; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Martinez-Lage M; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Abramson J; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Branagan AR; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Ji Y; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Chen YA; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Letourneau AR; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Nahed BV; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Arrillaga-Romany IC; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Wang N; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston., Dietrich J; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.
Source: Neurology [Neurology] 2024 Nov 12; Vol. 103 (9), pp. e209929. Date of Electronic Publication: 2024 Oct 04.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: Clinical Reasoning: Assessing New Neurologic Deficits in Patients With Hematologic Malignancy on Bruton Tyrosine Kinase Inhibitor Therapy.
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  Data: <searchLink fieldCode="AU" term="%22Nelson+TA%22">Nelson TA</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Murthy+NK%22">Murthy NK</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Martinez-Lage+M%22">Martinez-Lage M</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Abramson+J%22">Abramson J</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Branagan+AR%22">Branagan AR</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Ji+Y%22">Ji Y</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Chen+YA%22">Chen YA</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Letourneau+AR%22">Letourneau AR</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Nahed+BV%22">Nahed BV</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Arrillaga-Romany+IC%22">Arrillaga-Romany IC</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Dietrich+J%22">Dietrich J</searchLink>; From the Division of Neuro-Oncology (T.A.N., N.K.M., I.C.A.-R., N.W., J.D.), Department of Neurology; Department of Pathology (M.M.-L.A.); Division of Hematology and Oncology (J.A., A.R.B., Y.J., Y.-B.A.C.), Department of Medicine; Division of Infectious Diseases (A.R.L.), Department of Medicine; and Department of Neurosurgery (B.V.N.), Massachusetts General Hospital, Boston.
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