Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.

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Title: Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.
Authors: Edwards NC; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.; Department of Neuroscience, Columbia University, New York City, NY 10032, USA., Lao PJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Alshikho MJ; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Ericsson OM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Rizvi B; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA., Petersen ME; University of North Texas Health Science Center, Department of Pharmacology and Neuroscience, Fort Worth, TX 76107, USA., O'Bryant S; University of North Texas Health Science Center, Department of Pharmacology and Neuroscience, Fort Worth, TX 76107, USA., Aguilar LF; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA 92617, USA., Simoes S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Mapstone M; Department of Neurology, University of California, Irvine, CA 92697, USA., Tudorascu DL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund 221 00, Sweden., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund 221 00, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 214 28, Sweden., Handen BL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA., Christian BT; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Lee JH; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Lai F; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA., Rosas HD; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Radiology, Center for Neuroimaging of Aging and Neurodegenerative Diseases, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA., Zaman S; Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK., Lott IT; Department of Pediatrics and Neurology, School of Medicine, University of California, Irvine, CA 92868, USA., Yassa MA; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA., Gutierrez J; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA., Wilcock DM; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Head E; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA 92617, USA., Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.
Corporate Authors: Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC-DS) Investigators
Source: Brain communications [Brain Commun] 2024 Sep 25; Vol. 6 (5), pp. fcae331. Date of Electronic Publication: 2024 Sep 25 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
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  Data: Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Edwards+NC%22">Edwards NC</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.; Department of Neuroscience, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Lao+PJ%22">Lao PJ</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Alshikho+MJ%22">Alshikho MJ</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Ericsson+OM%22">Ericsson OM</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Rizvi+B%22">Rizvi B</searchLink>; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Petersen+ME%22">Petersen ME</searchLink>; University of North Texas Health Science Center, Department of Pharmacology and Neuroscience, Fort Worth, TX 76107, USA.<br /><searchLink fieldCode="AU" term="%22O'Bryant+S%22">O'Bryant S</searchLink>; University of North Texas Health Science Center, Department of Pharmacology and Neuroscience, Fort Worth, TX 76107, USA.<br /><searchLink fieldCode="AU" term="%22Aguilar+LF%22">Aguilar LF</searchLink>; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA 92617, USA.<br /><searchLink fieldCode="AU" term="%22Simoes+S%22">Simoes S</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Mapstone+M%22">Mapstone M</searchLink>; Department of Neurology, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Tudorascu+DL%22">Tudorascu DL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Janelidze+S%22">Janelidze S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund 221 00, Sweden.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund 221 00, Sweden.; Memory Clinic, Skåne University Hospital, Malmö 214 28, Sweden.<br /><searchLink fieldCode="AU" term="%22Handen+BL%22">Handen BL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Christian+BT%22">Christian BT</searchLink>; Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Lai+F%22">Lai F</searchLink>; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Rosas+HD%22">Rosas HD</searchLink>; Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Radiology, Center for Neuroimaging of Aging and Neurodegenerative Diseases, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Zaman+S%22">Zaman S</searchLink>; Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK.<br /><searchLink fieldCode="AU" term="%22Lott+IT%22">Lott IT</searchLink>; Department of Pediatrics and Neurology, School of Medicine, University of California, Irvine, CA 92868, USA.<br /><searchLink fieldCode="AU" term="%22Yassa+MA%22">Yassa MA</searchLink>; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA.; Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+J%22">Gutierrez J</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Wilcock+DM%22">Wilcock DM</searchLink>; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.<br /><searchLink fieldCode="AU" term="%22Head+E%22">Head E</searchLink>; Department of Pathology and Laboratory Medicine, University of California Irvine School of Medicine, University of California, Irvine, CA 92617, USA.<br /><searchLink fieldCode="AU" term="%22Brickman+AM%22">Brickman AM</searchLink>; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York City, NY 10032, USA.; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York City, NY 10032, USA.
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