The effects of denosumab on osteoclast precursors in postmenopausal women: a possible explanation for the overshoot phenomenon after discontinuation.

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Title: The effects of denosumab on osteoclast precursors in postmenopausal women: a possible explanation for the overshoot phenomenon after discontinuation.
Authors: Schini M; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.; Metabolic Bone Centre, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, United Kingdom., Gossiel F; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom., Saini T; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom., Banda P; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom., Ward R; Metabolic Bone Centre, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, United Kingdom., Vilaca T; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom., Eastell R; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom., Fontalis A; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.; Division of Surgery and Interventional Science, University College London, London, NW3 2PS, United Kingdom.
Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2025 Mar 15; Vol. 40 (3), pp. 301-306.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8610640 Publication Model: Print Cited Medium: Internet ISSN: 1523-4681 (Electronic) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The effects of denosumab on osteoclast precursors in postmenopausal women: a possible explanation for the overshoot phenomenon after discontinuation.
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  Data: <searchLink fieldCode="AU" term="%22Schini+M%22">Schini M</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.; Metabolic Bone Centre, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gossiel+F%22">Gossiel F</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Saini+T%22">Saini T</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Banda+P%22">Banda P</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ward+R%22">Ward R</searchLink>; Metabolic Bone Centre, Sheffield Teaching Hospitals, NHS Foundation Trust, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Vilaca+T%22">Vilaca T</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Eastell+R%22">Eastell R</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fontalis+A%22">Fontalis A</searchLink>; Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, S10 2RX, United Kingdom.; Division of Surgery and Interventional Science, University College London, London, NW3 2PS, United Kingdom.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8610640 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-4681 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208840431%22">08840431 </searchLink><i>NLM ISO Abbreviation: </i>J Bone Miner Res <i>Subsets: </i>MEDLINE
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        Value: 10.1093/jbmr/zjae170
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              Text: 2025 Mar 15
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