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Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?

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Title: Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?
Authors: Du R; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Zhang J; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Lukas RV; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Tripathi S; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Ahrendsen JT; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA (J.T.A.).; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Curran MA; Department of Immunology, MD Anderson Cancer Center, the University of Texas, Houston, Texas, USA., Dmello C; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Zhang P; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Stupp R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Rao G; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA., Heimberger AB; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Source: Neuro-oncology [Neuro Oncol] 2025 Jan 12; Vol. 27 (1), pp. 33-49.
Publication Type: Journal Article; Review
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Du+R%22">Du R</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Lukas+RV%22">Lukas RV</searchLink>; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Tripathi+S%22">Tripathi S</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Ahrendsen+JT%22">Ahrendsen JT</searchLink>; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA (J.T.A.).; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Curran+MA%22">Curran MA</searchLink>; Department of Immunology, MD Anderson Cancer Center, the University of Texas, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Dmello+C%22">Dmello C</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Stupp+R%22">Stupp R</searchLink>; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Rao+G%22">Rao G</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Heimberger+AB%22">Heimberger AB</searchLink>; Lou and Jean Malnati Brain Tumor Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
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              Text: 2025 Jan 12
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