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A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation.

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Title: A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation.
Authors: Ge AY; School of Medicine, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA., Arab A; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA., Dai R; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA., Navickas A; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Fish L; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Garcia K; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Asgharian H; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Goudreau J; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Lee S; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA., Keenan K; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA., Pappalardi MB; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA., McCabe MT; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA., Przybyla L; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Laboratory for Genomics Research, San Francisco, CA, 94158, USA., Goodarzi H; Arc Institute, Palo Alto, CA, 94304, USA. Hani@arcinstitute.org.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org., Gilbert LA; Arc Institute, Palo Alto, CA, 94304, USA. Luke@arcinstitute.org.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA. Luke@arcinstitute.org.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA. Luke@arcinstitute.org.
Source: Scientific reports [Sci Rep] 2024 Oct 29; Vol. 14 (1), pp. 25940. Date of Electronic Publication: 2024 Oct 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process
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  Data: A multiomics approach reveals RNA dynamics promote cellular sensitivity to DNA hypomethylation.
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  Data: <searchLink fieldCode="AU" term="%22Ge+AY%22">Ge AY</searchLink>; School of Medicine, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Arab+A%22">Arab A</searchLink>; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Dai+R%22">Dai R</searchLink>; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Navickas+A%22">Navickas A</searchLink>; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Fish+L%22">Fish L</searchLink>; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+K%22">Garcia K</searchLink>; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Asgharian+H%22">Asgharian H</searchLink>; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Goudreau+J%22">Goudreau J</searchLink>; Arc Institute, Palo Alto, CA, 94304, USA.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Keenan+K%22">Keenan K</searchLink>; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.<br /><searchLink fieldCode="AU" term="%22Pappalardi+MB%22">Pappalardi MB</searchLink>; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.<br /><searchLink fieldCode="AU" term="%22McCabe+MT%22">McCabe MT</searchLink>; Tumor Cell Targeting Research Unit, Research, GSK, Collegeville, PA, 19426, USA.<br /><searchLink fieldCode="AU" term="%22Przybyla+L%22">Przybyla L</searchLink>; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA.; Laboratory for Genomics Research, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Goodarzi+H%22">Goodarzi H</searchLink>; Arc Institute, Palo Alto, CA, 94304, USA. Hani@arcinstitute.org.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94158, USA. Hani@arcinstitute.org.<br /><searchLink fieldCode="AU" term="%22Gilbert+LA%22">Gilbert LA</searchLink>; Arc Institute, Palo Alto, CA, 94304, USA. Luke@arcinstitute.org.; Department of Urology, University of California, San Francisco, San Francisco, CA, 94158, USA. Luke@arcinstitute.org.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94158, USA. Luke@arcinstitute.org.
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