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Methylation Mesa define functional regulatory elements for targeted gene activation.

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Title: Methylation Mesa define functional regulatory elements for targeted gene activation.
Authors: Liu YV; Cancer Science Institute of Singapore, 117599, Singapore.; Genetic Perturbation Platform, Broad Institute, Cambridge, MA 02142, USA., Suryatenggara J; Cancer Science Institute of Singapore, 117599, Singapore., Wong H; Cancer Science Institute of Singapore, 117599, Singapore., Jayasinghe MK; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore., Tang JP; Cancer Science Institute of Singapore, 117599, Singapore., Tan HK; Cancer Science Institute of Singapore, 117599, Singapore., Kwon J; Cancer Science Institute of Singapore, 117599, Singapore., Zhou Q; Cancer Science Institute of Singapore, 117599, Singapore., Ummarino S; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA., Ebralidze AK; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA., Le MTN; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore., Doench JG; Genetic Perturbation Platform, Broad Institute, Cambridge, MA 02142, USA., Chai L; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA., Benoukraf T; Cancer Science Institute of Singapore, 117599, Singapore.; Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, A1B 3V6, Canada., Hiwase D; Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, South Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia., Thomas D; Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, South Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia., Di Ruscio A; Department of Translational Medicine, University of Eastern Piedmont, Novara, 28100, Italy.; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA, 02115, USA.; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, 330 Brookline Avenue Boston, MA 02215., Tenen DG; Cancer Science Institute of Singapore, 117599, Singapore.; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA, 02115, USA., Bassal MA; Cancer Science Institute of Singapore, 117599, Singapore.; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.
Source: Research square [Res Sq] 2024 Oct 16. Date of Electronic Publication: 2024 Oct 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Liu+YV%22">Liu YV</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.; Genetic Perturbation Platform, Broad Institute, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Suryatenggara+J%22">Suryatenggara J</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+H%22">Wong H</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Jayasinghe+MK%22">Jayasinghe MK</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore.<br /><searchLink fieldCode="AU" term="%22Tang+JP%22">Tang JP</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+HK%22">Tan HK</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Kwon+J%22">Kwon J</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Ummarino+S%22">Ummarino S</searchLink>; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.<br /><searchLink fieldCode="AU" term="%22Ebralidze+AK%22">Ebralidze AK</searchLink>; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.<br /><searchLink fieldCode="AU" term="%22Le+MTN%22">Le MTN</searchLink>; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore.<br /><searchLink fieldCode="AU" term="%22Doench+JG%22">Doench JG</searchLink>; Genetic Perturbation Platform, Broad Institute, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Chai+L%22">Chai L</searchLink>; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Benoukraf+T%22">Benoukraf T</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.; Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, A1B 3V6, Canada.<br /><searchLink fieldCode="AU" term="%22Hiwase+D%22">Hiwase D</searchLink>; Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, South Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia.<br /><searchLink fieldCode="AU" term="%22Thomas+D%22">Thomas D</searchLink>; Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, South Australia.; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia.<br /><searchLink fieldCode="AU" term="%22Di+Ruscio+A%22">Di Ruscio A</searchLink>; Department of Translational Medicine, University of Eastern Piedmont, Novara, 28100, Italy.; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA, 02115, USA.; Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, 330 Brookline Avenue Boston, MA 02215.<br /><searchLink fieldCode="AU" term="%22Tenen+DG%22">Tenen DG</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.; Harvard Medical School Initiative for RNA Medicine, Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Bassal+MA%22">Bassal MA</searchLink>; Cancer Science Institute of Singapore, 117599, Singapore.; Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115 USA.
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