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Low-dose IL-2 in birch pollen allergy: A phase-2 randomized double-blind placebo-controlled trial.

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Title: Low-dose IL-2 in birch pollen allergy: A phase-2 randomized double-blind placebo-controlled trial.
Authors: Rosenzwajg M; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France., Gherasim A; Centre de recherche clinique ALYATEC, Strasbourg, France., Dietsch F; Centre de recherche clinique ALYATEC, Strasbourg, France., Beck M; Centre de recherche clinique ALYATEC, Strasbourg, France., Domis N; Centre de recherche clinique ALYATEC, Strasbourg, France., Lorenzon R; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France., Chantran Y; Immunology Department, Saint Antoine Hospital, AP-HP, Paris, France., Bellier B; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France., Vicaut E; Unité de recherche clinique, Saint Louis/Lariboisière Hospitals, AP-HP, and Université Paris 7, Paris, France., Soria A; Dermatology and Allergy Department, Tenon Hospital, AP-HP, Paris., de Blay F; Centre de recherche clinique ALYATEC, Strasbourg, France., Klatzmann D; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France. Electronic address: david.klatzmann@sorbonne-universite.fr.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2025 Feb; Vol. 155 (2), pp. 650-655. Date of Electronic Publication: 2024 Nov 10.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Low-dose IL-2 in birch pollen allergy: A phase-2 randomized double-blind placebo-controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Rosenzwajg+M%22">Rosenzwajg M</searchLink>; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gherasim+A%22">Gherasim A</searchLink>; Centre de recherche clinique ALYATEC, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Dietsch+F%22">Dietsch F</searchLink>; Centre de recherche clinique ALYATEC, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Beck+M%22">Beck M</searchLink>; Centre de recherche clinique ALYATEC, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Domis+N%22">Domis N</searchLink>; Centre de recherche clinique ALYATEC, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Lorenzon+R%22">Lorenzon R</searchLink>; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chantran+Y%22">Chantran Y</searchLink>; Immunology Department, Saint Antoine Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bellier+B%22">Bellier B</searchLink>; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France.<br /><searchLink fieldCode="AU" term="%22Vicaut+E%22">Vicaut E</searchLink>; Unité de recherche clinique, Saint Louis/Lariboisière Hospitals, AP-HP, and Université Paris 7, Paris, France.<br /><searchLink fieldCode="AU" term="%22Soria+A%22">Soria A</searchLink>; Dermatology and Allergy Department, Tenon Hospital, AP-HP, Paris.<br /><searchLink fieldCode="AU" term="%22de+Blay+F%22">de Blay F</searchLink>; Centre de recherche clinique ALYATEC, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Klatzmann+D%22">Klatzmann D</searchLink>; Biotherapy Clinical Investigation Center (CIC-BTi) and Inflammation-Immunopathology-Immunotherapy Department (i2B), Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Immunology-Immunopathology-Immunotherapy, Sorbonne Université, INSERM, UMR_S 959, Paris, France. Electronic address: david.klatzmann@sorbonne-universite.fr.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2025 Feb; Vol. 155 (2), pp. 650-655. <i>Date of Electronic Publication: </i>2024 Nov 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
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              Text: 2025 Feb
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