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The potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial.

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Title: The potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial.
Authors: Judge PK; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Tuttle KR; Providence Inland Northwest Health, Spokane, WA and University of Washington, Seattle, WA, USA., Staplin N; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Hauske SJ; Boehringer Ingelheim International GmbH, Ingelheim, Germany.; Vth Department of Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany., Zhu D; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Sardell R; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Cronin L; Boehringer Ingelheim International GmbH, Ingelheim, Germany., Green JB; Duke Clinical Research Institute, Durham, NC, USA., Agrawal N; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Arimoto R; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Mayne KJ; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; School of Cardiovascular and Metabolic Health, College of Medical and Veterinary Life Sciences, University of Glasgow, Glasgow, UK., Sammons E; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Brueckmann M; Boehringer Ingelheim International GmbH, Ingelheim, Germany.; Ist Department of Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany., Shah SV; Boehringer Ingelheim International GmbH, Ingelheim, Germany., Rossing P; Steno Diabetes Center Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Nangaku M; Division of Nephrology and Endocrinology, University of Tokyo Hospital, Tokyo, Japan., Landray MJ; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Wanner C; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; University Clinic of Würzburg, Würzburg, Germany., Baigent C; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Haynes R; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Herrington WG; Renal Studies Group, Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2025 May 30; Vol. 40 (6), pp. 1175-1186.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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