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The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.

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Title: The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.
Authors: Singh SP; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Rajasthan, 333031, India., Smyth DJ; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Division of Cell Signalling and Immunology, University of Dundee, Dundee, UK., Cunningham KT; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK., Mukundan A; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Byeon CH; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Hinck CS; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., White MPJ; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Gillies McIndoe Research Institute, Wellington, New Zealand., Ciancia C; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK., Wąsowska N; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Leiden University Medical Center, Leiden, The Netherlands., Sanders A; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK., Jin R; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., White RF; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK., Lilla S; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK., Zanivan S; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Schoenherr C; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK., Inman GJ; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, The Netherlands., Ten Dijke P; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, The Netherlands., Hinck AP; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA., Maizels RM; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK. rick.maizels@glasgow.ac.uk.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Rajasthan, 333031, India. rick.maizels@glasgow.ac.uk.
Source: EMBO reports [EMBO Rep] 2025 Jan; Vol. 26 (1), pp. 218-244. Date of Electronic Publication: 2024 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Singh+SP%22">Singh SP</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Rajasthan, 333031, India.<br /><searchLink fieldCode="AU" term="%22Smyth+DJ%22">Smyth DJ</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Division of Cell Signalling and Immunology, University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Cunningham+KT%22">Cunningham KT</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.<br /><searchLink fieldCode="AU" term="%22Mukundan+A%22">Mukundan A</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Byeon+CH%22">Byeon CH</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Hinck+CS%22">Hinck CS</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22White+MPJ%22">White MPJ</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Gillies McIndoe Research Institute, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Ciancia+C%22">Ciancia C</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.<br /><searchLink fieldCode="AU" term="%22Wąsowska+N%22">Wąsowska N</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sanders+A%22">Sanders A</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.<br /><searchLink fieldCode="AU" term="%22Jin+R%22">Jin R</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.; Center for Cancer Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22White+RF%22">White RF</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK.<br /><searchLink fieldCode="AU" term="%22Lilla+S%22">Lilla S</searchLink>; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Zanivan+S%22">Zanivan S</searchLink>; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Schoenherr+C%22">Schoenherr C</searchLink>; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Inman+GJ%22">Inman GJ</searchLink>; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22van+Dinther+M%22">van Dinther M</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ten+Dijke+P%22">Ten Dijke P</searchLink>; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hinck+AP%22">Hinck AP</searchLink>; Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Maizels+RM%22">Maizels RM</searchLink>; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, G12 8TA, UK. rick.maizels@glasgow.ac.uk.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Rajasthan, 333031, India. rick.maizels@glasgow.ac.uk.
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