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Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.

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Title: Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Authors: Wang ZQ; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Wu ZX; Department of Colorectal Surgery, Sir Run Shaw Hospital of Zhejiang University, Hangzhou, Zhejiang 310016, PR China., Chen JW; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Li HF; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Wu HD; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Bao JX; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Cheng Y; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Dai YW; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China., Wang OC; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China; Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, PR China. Electronic address: woc@wmu.edu.cn., Dai XX; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China; Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, PR China. Electronic address: daoshidaixuanxuan@126.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Jan; Vol. 136, pp. 156287. Date of Electronic Publication: 2024 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
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  Data: <searchLink fieldCode="AU" term="%22Wang+ZQ%22">Wang ZQ</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Wu+ZX%22">Wu ZX</searchLink>; Department of Colorectal Surgery, Sir Run Shaw Hospital of Zhejiang University, Hangzhou, Zhejiang 310016, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+JW%22">Chen JW</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Li+HF%22">Li HF</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Wu+HD%22">Wu HD</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Bao+JX%22">Bao JX</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Dai+YW%22">Dai YW</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+OC%22">Wang OC</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China; Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, PR China. Electronic address: woc@wmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Dai+XX%22">Dai XX</searchLink>; Department of Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, PR China; Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325035, PR China. Electronic address: daoshidaixuanxuan@126.com.
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  Data: <searchLink fieldCode="JN" term="%229438794%22">Phytomedicine : international journal of phytotherapy and phytopharmacology</searchLink> [Phytomedicine] 2025 Jan; Vol. 136, pp. 156287. <i>Date of Electronic Publication: </i>2024 Nov 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Urban+%26+Fischer+Verlag%22">Urban & Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9438794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-095X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209447113%22">09447113 </searchLink><i>NLM ISO Abbreviation: </i>Phytomedicine <i>Subsets: </i>MEDLINE
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              Text: 2025 Jan
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