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Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.

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Title: Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
Authors: Gorman BR; Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Voloudakis G; Center for Disease Neurogenomics, Department of Psychiatry; Friedman Brain Institute; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Precision Medicine and Translational Therapeutics, VISN 2 Mental Illness Research, Education, and Clinical Center (MIRECC), James J. Peters Veterans Affairs Medical Center, New York/New Jersey VA Health Care Network, Bronx, NY, USA., Igo RP Jr; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Kinzy T; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Halladay CW; Center of Innovation in Long Term Services and Supports, VA Providence Healthcare System, Providence, RI, USA., Bigdeli TB; Research Service, VA New York Harbor Healthcare System, Brooklyn, NY, USA.; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA., Zeng B; Center for Disease Neurogenomics, Department of Psychiatry; Friedman Brain Institute; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Venkatesh S; Center for Disease Neurogenomics, Department of Psychiatry; Friedman Brain Institute; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Precision Medicine and Translational Therapeutics, VISN 2 Mental Illness Research, Education, and Clinical Center (MIRECC), James J. Peters Veterans Affairs Medical Center, New York/New Jersey VA Health Care Network, Bronx, NY, USA., Cooke Bailey JN; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.; Department of Genetics & Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Crawford DC; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.; Department of Genetics & Genome Sciences, Case Western Reserve University, Cleveland, OH, USA., Markianos K; Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA., Dong F; Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Schreiner PA; Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.; Booz Allen Hamilton, McLean, VA, USA., Zhang W; Center for Disease Neurogenomics, Department of Psychiatry; Friedman Brain Institute; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hadi T; Eye Clinic, VA Northeast Ohio Healthcare System, Cleveland, OH, USA.; Department of Ophthalmology and Visual Sciences, University Hospitals Eye Institute, Cleveland, OH, USA., Anger MD; Eye Clinic, VA Western NY Healthcare System, Buffalo, NY, USA.; Ophthalmology, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA., Stockwell A; Department of Human Genetics, Genentech, South San Francisco, CA, USA., Melles RB; Department of Ophthalmology, Kaiser Permanente Northern California, Redwood City, CA, USA., Yin J; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Kaye R; Southampton Eye Unit, University Hospital Southampton National Health Service Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Patasova K; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Patel PJ; National Institute for Health and Care Research Biomedical Research Centre, Moorfields Eye Hospital National Health Service Foundation Trust, London, UK.; Institute of Ophthalmology, University College London, London, UK., Yaspan BL; Department of Human Genetics, Genentech, South San Francisco, CA, USA., Jorgenson E; Regeneron Genetics Center, Tarrytown, NY, USA., Hysi PG; Section of Ophthalmology, School of Life Course Sciences, King's College London, London, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; UCL Great Ormond Street Institute of Child Health, King's College London, London, UK.; Sørlandet Sykehus Arendal, Arendal Hospital, Arendal, Norway., Lotery AJ; Southampton Eye Unit, University Hospital Southampton National Health Service Foundation Trust, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Gaziano JM; Million Veteran Program Coordinating Center, VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Tsao PS; VA Palo Alto Epidemiology Research and Information Center for Genomics, VA Palo Alto Health Care System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Fliesler SJ; Ophthalmology, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA.; Research Service, VA Western NY Healthcare System, Buffalo, NY, USA.; Biochemistry, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA.; Graduate Program in Neurosciences, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA., Sullivan JM; Ophthalmology, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA.; Research Service, VA Western NY Healthcare System, Buffalo, NY, USA.; Graduate Program in Neurosciences, Jacobs School of Medicine and Biomedical Sciences, SUNY-University at Buffalo, Buffalo, NY, USA., Greenberg PB; Section of Ophthalmology, VA Providence Healthcare System, Providence, RI, USA.; Division of Ophthalmology, Alpert Medical School, Brown University, Providence, RI, USA., Wu WC; Section of Cardiology, Medical Service, VA Providence Healthcare System, Providence, RI, USA.; Division of Cardiology, Department of Medicine, Alpert Medical School, Brown University, Providence, RI, USA., Assimes TL; VA Palo Alto Epidemiology Research and Information Center for Genomics, VA Palo Alto Health Care System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Pyarajan S; Center for Data and Computational Sciences (C-DACS), VA Cooperative Studies Program, VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Roussos P; Center for Disease Neurogenomics, Department of Psychiatry; Friedman Brain Institute; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. panagiotis.roussos@mssm.edu.; Center for Precision Medicine and Translational Therapeutics, VISN 2 Mental Illness Research, Education, and Clinical Center (MIRECC), James J. Peters Veterans Affairs Medical Center, New York/New Jersey VA Health Care Network, Bronx, NY, USA. panagiotis.roussos@mssm.edu., Peachey NS; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA. neal.peachey@va.gov.; Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA. neal.peachey@va.gov.; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA. neal.peachey@va.gov., Iyengar SK; Research Service, VA Northeast Ohio Healthcare System, Cleveland, OH, USA. ski@case.edu.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA. ski@case.edu.; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. ski@case.edu.; Department of Genetics & Genome Sciences, Case Western Reserve University, Cleveland, OH, USA. ski@case.edu.; Department of Ophthalmology and Visual Sciences, University Hospitals Eye Institute, Cleveland, OH, USA. ski@case.edu.
Corporate Authors: VA Million Veteran Program, International AMD Genomics Consortium (IAMDGC)
Source: Nature genetics [Nat Genet] 2024 Dec; Vol. 56 (12), pp. 2659-2671. Date of Electronic Publication: 2024 Dec 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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  Data: Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries.
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            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 56
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1