High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma.
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| Title: | High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma. |
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| Authors: | Cho SH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Park JM; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Lee EH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Song YH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Jang YJ; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Choi SB; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Heo YS; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea. Electronic address: ysheo@konkuk.ac.kr. |
| Source: | Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Jan; Vol. 742, pp. 151106. Date of Electronic Publication: 2024 Nov 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39632294 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cho+SH%22">Cho SH</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JM%22">Park JM</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+EH%22">Lee EH</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Song+YH%22">Song YH</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+YJ%22">Jang YJ</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SB%22">Choi SB</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+YS%22">Heo YS</searchLink>; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea. Electronic address: ysheo@konkuk.ac.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220372516%22">Biochemical and biophysical research communications</searchLink> [Biochem Biophys Res Commun] 2025 Jan; Vol. 742, pp. 151106. <i>Date of Electronic Publication: </i>2024 Nov 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372516 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2104 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220006291X%22">0006291X </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Res Commun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39632294 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bbrc.2024.151106 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 151106 Titles: – TitleFull: High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cho SH – PersonEntity: Name: NameFull: Park JM – PersonEntity: Name: NameFull: Lee EH – PersonEntity: Name: NameFull: Song YH – PersonEntity: Name: NameFull: Jang YJ – PersonEntity: Name: NameFull: Choi SB – PersonEntity: Name: NameFull: Heo YS IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2025 Jan Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1090-2104 Numbering: – Type: volume Value: 742 Titles: – TitleFull: Biochemical and biophysical research communications Type: main |
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