High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma.
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| Title: | High-resolution crystal structure of PD-1 in complex with retifanlimab, the FDA-approved immune checkpoint blocking antibody for treating Merkel cell carcinoma. |
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| Authors: | Cho SH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Park JM; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Lee EH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Song YH; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Jang YJ; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Choi SB; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea., Heo YS; Department of Chemistry, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029. Republic of Korea, Republic of Korea. Electronic address: ysheo@konkuk.ac.kr. |
| Source: | Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Jan; Vol. 742, pp. 151106. Date of Electronic Publication: 2024 Nov 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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