Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.

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Title: Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
Authors: De Felice D; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Alaimo A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Bressan D; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Genovesi S; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Marmocchi E; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Annesi N; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Beccaceci G; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Dalfovo D; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Cutrupi F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Medaglia S; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Foletto V; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Lorenzoni M; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Gandolfi F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Kannan S; Bioinformatics Institute (Agency for Science, Technology and Research, A*STAR), 30 Biopolis Street, 07-01 Matrix, Singapore, 138671, Singapore., Verma CS; Bioinformatics Institute (Agency for Science, Technology and Research, A*STAR), 30 Biopolis Street, 07-01 Matrix, Singapore, 138671, Singapore.; Department of Biological Sciences, National University of Singapore, 14 Science Drive, Singapore, 117543, Singapore.; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore., Vasciaveo A; Departments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Shen MM; Departments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Romanel A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Chiacchiera F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy., Cambuli F; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy. francesco.cambuli@fht.org.; Human Technopole, via Rita Levi Montalcini 1, Milan, Italy. francesco.cambuli@fht.org., Lunardi A; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy. andrea.lunardi@unitn.it.
Source: EMBO reports [EMBO Rep] 2025 Jan; Vol. 26 (2), pp. 443-469. Date of Electronic Publication: 2024 Dec 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
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  Data: Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.
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  Data: <searchLink fieldCode="AU" term="%22De+Felice+D%22">De Felice D</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Alaimo+A%22">Alaimo A</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Bressan+D%22">Bressan D</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Genovesi+S%22">Genovesi S</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Marmocchi+E%22">Marmocchi E</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Annesi+N%22">Annesi N</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Beccaceci+G%22">Beccaceci G</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Dalfovo+D%22">Dalfovo D</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Cutrupi+F%22">Cutrupi F</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Medaglia+S%22">Medaglia S</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Foletto+V%22">Foletto V</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Lorenzoni+M%22">Lorenzoni M</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Gandolfi+F%22">Gandolfi F</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Kannan+S%22">Kannan S</searchLink>; Bioinformatics Institute (Agency for Science, Technology and Research, A*STAR), 30 Biopolis Street, 07-01 Matrix, Singapore, 138671, Singapore.<br /><searchLink fieldCode="AU" term="%22Verma+CS%22">Verma CS</searchLink>; Bioinformatics Institute (Agency for Science, Technology and Research, A*STAR), 30 Biopolis Street, 07-01 Matrix, Singapore, 138671, Singapore.; Department of Biological Sciences, National University of Singapore, 14 Science Drive, Singapore, 117543, Singapore.; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore.<br /><searchLink fieldCode="AU" term="%22Vasciaveo+A%22">Vasciaveo A</searchLink>; Departments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Shen+MM%22">Shen MM</searchLink>; Departments of Medicine, Genetics & Development, Urology and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, USA.<br /><searchLink fieldCode="AU" term="%22Romanel+A%22">Romanel A</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Chiacchiera+F%22">Chiacchiera F</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy.<br /><searchLink fieldCode="AU" term="%22Cambuli+F%22">Cambuli F</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy. francesco.cambuli@fht.org.; Human Technopole, via Rita Levi Montalcini 1, Milan, Italy. francesco.cambuli@fht.org.<br /><searchLink fieldCode="AU" term="%22Lunardi+A%22">Lunardi A</searchLink>; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Trento, TN, Italy. andrea.lunardi@unitn.it.
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