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Efficacy and safety of risankizumab versus methotrexate in patients with moderate-to-severe plaque psoriasis: results from IMMbrace, a randomized, double-blind, phase 3 study with an open-label extension period in Brazil.

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Title: Efficacy and safety of risankizumab versus methotrexate in patients with moderate-to-severe plaque psoriasis: results from IMMbrace, a randomized, double-blind, phase 3 study with an open-label extension period in Brazil.
Authors: Cestari TF; Department of Dermatology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: tcestari@hcpa.edu.br., Souza CDS; Division of Dermatology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil., Azulay-Abulafia L; Instituto de Dermatologia e Estética do Rio de Janeiro, Rio de Janeiro, Brazil., Romiti R; Department of Dermatology, Hospital das Clínicas, Universidade de São Paulo, São Paulo, SP, Brazil., Carvalho AVE; Department of Dermatology, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil., Silva de Castro CC; Discipline of Dermatology, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil., Marques SA; Department of Infectology, Dermatology, Imaging Diagnosis and Radiotherapy, Faculty of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil., Antonio JR; Discipline of Dermatology, Faculdade Estadual de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil., Fabrício L; Dermaology Service, Hospital Universitário Evangélico Mackenzie de Curitiba, Curitiba, PR, Brazil., Soliman AM; AbbVie Inc., North Chicago, Illinois, United States., Wu T; AbbVie Inc., North Chicago, Illinois, United States., Sinvhal R; AbbVie Inc., North Chicago, Illinois, United States., Stakias V; AbbVie Inc., North Chicago, Illinois, United States., Song AP; AbbVie Inc., North Chicago, Illinois, United States., Kalabic J; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany., Martin N; AbbVie Inc., North Chicago, Illinois, United States; In memoriam., Oyafuso LKM; Department of Dermatology, Faculdade de Medicina de ABC, São Paulo, SP, Brazil.
Source: Anais brasileiros de dermatologia [An Bras Dermatol] 2025 Mar-Apr; Vol. 100 (2), pp. 260-271. Date of Electronic Publication: 2024 Dec 07.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Elsevier España, S.L Country of Publication: Spain NLM ID: 0067662 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1806-4841 (Electronic) Linking ISSN: 03650596 NLM ISO Abbreviation: An Bras Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of risankizumab versus methotrexate in patients with moderate-to-severe plaque psoriasis: results from IMMbrace, a randomized, double-blind, phase 3 study with an open-label extension period in Brazil.
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  Data: <searchLink fieldCode="AU" term="%22Cestari+TF%22">Cestari TF</searchLink>; Department of Dermatology, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: tcestari@hcpa.edu.br.<br /><searchLink fieldCode="AU" term="%22Souza+CDS%22">Souza CDS</searchLink>; Division of Dermatology, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Azulay-Abulafia+L%22">Azulay-Abulafia L</searchLink>; Instituto de Dermatologia e Estética do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Romiti+R%22">Romiti R</searchLink>; Department of Dermatology, Hospital das Clínicas, Universidade de São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+AVE%22">Carvalho AVE</searchLink>; Department of Dermatology, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+de+Castro+CC%22">Silva de Castro CC</searchLink>; Discipline of Dermatology, Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.<br /><searchLink fieldCode="AU" term="%22Marques+SA%22">Marques SA</searchLink>; Department of Infectology, Dermatology, Imaging Diagnosis and Radiotherapy, Faculty of Medicine, Universidade Estadual Paulista, Botucatu, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Antonio+JR%22">Antonio JR</searchLink>; Discipline of Dermatology, Faculdade Estadual de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Fabrício+L%22">Fabrício L</searchLink>; Dermaology Service, Hospital Universitário Evangélico Mackenzie de Curitiba, Curitiba, PR, Brazil.<br /><searchLink fieldCode="AU" term="%22Soliman+AM%22">Soliman AM</searchLink>; AbbVie Inc., North Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; AbbVie Inc., North Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Sinvhal+R%22">Sinvhal R</searchLink>; AbbVie Inc., North Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Stakias+V%22">Stakias V</searchLink>; AbbVie Inc., North Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Song+AP%22">Song AP</searchLink>; AbbVie Inc., North Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Kalabic+J%22">Kalabic J</searchLink>; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Martin+N%22">Martin N</searchLink>; AbbVie Inc., North Chicago, Illinois, United States; In memoriam.<br /><searchLink fieldCode="AU" term="%22Oyafuso+LKM%22">Oyafuso LKM</searchLink>; Department of Dermatology, Faculdade de Medicina de ABC, São Paulo, SP, Brazil.
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  Data: <searchLink fieldCode="JN" term="%220067662%22">Anais brasileiros de dermatologia</searchLink> [An Bras Dermatol] 2025 Mar-Apr; Vol. 100 (2), pp. 260-271. <i>Date of Electronic Publication: </i>2024 Dec 07.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+España%2C+S%2EL%22">Elsevier España, S.L </searchLink><i>Country of Publication: </i>Spain <i>NLM ID: </i>0067662 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1806-4841 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203650596%22">03650596 </searchLink><i>NLM ISO Abbreviation: </i>An Bras Dermatol <i>Subsets: </i>MEDLINE
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