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Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice.

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Title: Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice.
Authors: Isola JVV; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Biswas S; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Jayarathne H; Department of Biological Sciences, Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, MI, 48202, USA., Hubbart CR; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Hense JD; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Matsuzaki S; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Kinter MT; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Humphries KM; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA., Ocañas SR; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA., Sadagurski M; Department of Biological Sciences, Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, MI, 48202, USA., Stout MB; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA. michael-stout@omrf.org.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA. michael-stout@omrf.org.
Source: GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 3061-3076. Date of Electronic Publication: 2024 Dec 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Canagliflozin treatment prevents follicular exhaustion and attenuates hallmarks of ovarian aging in genetically heterogenous mice.
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  Data: <searchLink fieldCode="AU" term="%22Isola+JVV%22">Isola JVV</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Biswas+S%22">Biswas S</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Jayarathne+H%22">Jayarathne H</searchLink>; Department of Biological Sciences, Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, MI, 48202, USA.<br /><searchLink fieldCode="AU" term="%22Hubbart+CR%22">Hubbart CR</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Hense+JD%22">Hense JD</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Matsuzaki+S%22">Matsuzaki S</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Kinter+MT%22">Kinter MT</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Humphries+KM%22">Humphries KM</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA.<br /><searchLink fieldCode="AU" term="%22Ocañas+SR%22">Ocañas SR</searchLink>; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Sadagurski+M%22">Sadagurski M</searchLink>; Department of Biological Sciences, Institute of Environmental Health Sciences, Integrative Biosciences Center, Wayne State University, Detroit, MI, 48202, USA.<br /><searchLink fieldCode="AU" term="%22Stout+MB%22">Stout MB</searchLink>; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, 825 NE 13 Street, Chapman E306, Oklahoma City, OK, 73104, USA. michael-stout@omrf.org.; Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK, USA. michael-stout@omrf.org.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2025 Jun; Vol. 47 (3), pp. 3061-3076. <i>Date of Electronic Publication: </i>2024 Dec 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE
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              Text: 2025 Jun
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