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Meta-Analysis of Transcriptomic Studies of Blood and Six Brain Regions Identifies a Consensus of 15 Cross-Tissue Mechanisms in Alzheimer's Disease and Suggests an Origin of Cross-Study Heterogeneity.

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Title: Meta-Analysis of Transcriptomic Studies of Blood and Six Brain Regions Identifies a Consensus of 15 Cross-Tissue Mechanisms in Alzheimer's Disease and Suggests an Origin of Cross-Study Heterogeneity.
Authors: Hou J; Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Hess JL; Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Zhang C; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York, USA., van Rooij JGJ; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands., Hearn GC; Norton College of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA., Fan CC; Department of Cognitive Science, University of California San Diego, La Jolla, California, USA., Faraone SV; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York, USA.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Fennema-Notestine C; Department of Psychiatry, University of California San Diego, La Jolla, California, USA.; Department of Radiology, University of California San Diego, La Jolla, California, USA., Lin SJ; Department of Psychiatry, University of California San Diego, La Jolla, California, USA., Escott-Price V; Dementia Research Institute, School of Medicine, Cardiff University, Cardiff, UK.; Division of Psychological Medicine and Clinical Neurology and Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK., Seshadri S; Department of Neurology, School of Medicine, Boston University, Boston, Massachusetts, USA., Holmans P; Division of Psychological Medicine and Clinical Neurology and Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK., Tsuang MT; Department of Psychiatry, University of California San Diego, La Jolla, California, USA., Kremen WS; Department of Psychiatry, University of California San Diego, La Jolla, California, USA., Gaiteri C; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Glatt SJ; Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab), Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA.; Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York, USA.; Department of Public Health and Preventive Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
Corporate Authors: Alzheimer's Disease Neuroimaging Initiative
Source: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [Am J Med Genet B Neuropsychiatr Genet] 2025 Jun; Vol. 198 (4), pp. e33019. Date of Electronic Publication: 2024 Dec 16.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-485X (Electronic) Linking ISSN: 15524841 NLM ISO Abbreviation: Am J Med Genet B Neuropsychiatr Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Meta-Analysis of Transcriptomic Studies of Blood and Six Brain Regions Identifies a Consensus of 15 Cross-Tissue Mechanisms in Alzheimer's Disease and Suggests an Origin of Cross-Study Heterogeneity.
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