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Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease.

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Title: Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease.
Authors: Li Y; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA., Serras CP; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA., Blumenfeld J; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Neuroscience Graduate Program, University of California, San Francisco, CA, USA., Xie M; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA., Hao Y; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA., Deng E; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA., Chun YY; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA., Holtzman J; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA., An A; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA., Yoon SY; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA., Tang X; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Rao A; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Developmental and Stem Cell Biology Graduate Program, University of California, San Francisco, CA, USA., Woldemariam S; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Tang A; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Bioengineering Graduate Program, University of California, San Francisco and University of California, Berkeley, CA, USA., Zhang A; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA., Simms J; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA., Lo I; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA., Oskotsky T; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Keiser MJ; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA., Huang Y; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Neuroscience Graduate Program, University of California, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA.; Developmental and Stem Cell Biology Graduate Program, University of California, San Francisco, CA, USA.; Departments of Neurology and Pathology, University of California, San Francisco, San Francisco, CA, USA., Sirota M; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Dec 13. Date of Electronic Publication: 2024 Dec 13.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Data-driven discovery of cell-type-directed network-correcting combination therapy for Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Serras+CP%22">Serras CP</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blumenfeld+J%22">Blumenfeld J</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Neuroscience Graduate Program, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xie+M%22">Xie M</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hao+Y%22">Hao Y</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Deng+E%22">Deng E</searchLink>; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chun+YY%22">Chun YY</searchLink>; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+J%22">Holtzman J</searchLink>; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22An+A%22">An A</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yoon+SY%22">Yoon SY</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rao+A%22">Rao A</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Developmental and Stem Cell Biology Graduate Program, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Woldemariam+S%22">Woldemariam S</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tang+A%22">Tang A</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Bioengineering Graduate Program, University of California, San Francisco and University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+A%22">Zhang A</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Simms+J%22">Simms J</searchLink>; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lo+I%22">Lo I</searchLink>; Gladstone Behavior Core, Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Oskotsky+T%22">Oskotsky T</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Keiser+MJ%22">Keiser MJ</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA.; Neuroscience Graduate Program, University of California, San Francisco, CA, USA.; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA, USA.; Developmental and Stem Cell Biology Graduate Program, University of California, San Francisco, CA, USA.; Departments of Neurology and Pathology, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sirota+M%22">Sirota M</searchLink>; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.; Pharmaceutical Science and Pharmacogenomics Graduate Program, University of California, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2024 Dec 13. <i>Date of Electronic Publication: </i>2024 Dec 13.
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        Value: 10.1101/2024.12.09.627436
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        Text: English
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