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FBP1 controls liver cancer evolution from senescent MASH hepatocytes.

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Title: FBP1 controls liver cancer evolution from senescent MASH hepatocytes.
Authors: Gu L; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA. ligu@scu.edu.cn.; Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China. ligu@scu.edu.cn.; Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China. ligu@scu.edu.cn., Zhu Y; School of Medicine, Chongqing University, Chongqing, China. zhuyahui861106@foxmail.com.; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. zhuyahui861106@foxmail.com., Nandi SP; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, USA.; Department of Bioengineering, UCSD, La Jolla, CA, USA.; Moores Cancer Center, UCSD, La Jolla, CA, USA., Lee M; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA., Watari K; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA., Bareng B; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA., Ohira M; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA., Liu Y; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA., Sakane S; Division of Endocrinology & Metabolism, UCSD, La Jolla, CA, USA., Carlessi R; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia.; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia., Sauceda C; Department of Pharmacology, UCSD, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA, USA., Dhar D; Department of Medicine, UCSD, La Jolla, CA, USA., Ganguly S; Department of Medicine, UCSD, La Jolla, CA, USA., Hosseini M; Department of Pathology, UCSD, La Jolla, CA, USA., Teneche MG; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Adams PD; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Gonzalez DJ; Department of Pharmacology, UCSD, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA, USA., Kisseleva T; Division of Endocrinology & Metabolism, UCSD, La Jolla, CA, USA., Tirnitz-Parker JEE; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia.; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia., Simon MC; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Alexandrov LB; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, USA.; Department of Bioengineering, UCSD, La Jolla, CA, USA.; Moores Cancer Center, UCSD, La Jolla, CA, USA., Karin M; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA. karinoffice@ucsd.edu.
Corporate Authors: Liver Cancer Collaborative
Source: Nature [Nature] 2025 Jan; Vol. 637 (8045), pp. 461-469. Date of Electronic Publication: 2025 Jan 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FBP1 controls liver cancer evolution from senescent MASH hepatocytes.
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  Data: <searchLink fieldCode="AU" term="%22Gu+L%22">Gu L</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA. ligu@scu.edu.cn.; Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China. ligu@scu.edu.cn.; Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China. ligu@scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; School of Medicine, Chongqing University, Chongqing, China. zhuyahui861106@foxmail.com.; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. zhuyahui861106@foxmail.com.<br /><searchLink fieldCode="AU" term="%22Nandi+SP%22">Nandi SP</searchLink>; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, USA.; Department of Bioengineering, UCSD, La Jolla, CA, USA.; Moores Cancer Center, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Watari+K%22">Watari K</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bareng+B%22">Bareng B</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ohira+M%22">Ohira M</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sakane+S%22">Sakane S</searchLink>; Division of Endocrinology & Metabolism, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Carlessi+R%22">Carlessi R</searchLink>; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia.; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Sauceda+C%22">Sauceda C</searchLink>; Department of Pharmacology, UCSD, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dhar+D%22">Dhar D</searchLink>; Department of Medicine, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ganguly+S%22">Ganguly S</searchLink>; Department of Medicine, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hosseini+M%22">Hosseini M</searchLink>; Department of Pathology, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Teneche+MG%22">Teneche MG</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Adams+PD%22">Adams PD</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez+DJ%22">Gonzalez DJ</searchLink>; Department of Pharmacology, UCSD, La Jolla, CA, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kisseleva+T%22">Kisseleva T</searchLink>; Division of Endocrinology & Metabolism, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tirnitz-Parker+JEE%22">Tirnitz-Parker JEE</searchLink>; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, Western Australia, Australia.; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Nedlands, Western Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Simon+MC%22">Simon MC</searchLink>; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Alexandrov+LB%22">Alexandrov LB</searchLink>; Department of Cellular and Molecular Medicine, UCSD, La Jolla, CA, USA.; Department of Bioengineering, UCSD, La Jolla, CA, USA.; Moores Cancer Center, UCSD, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Karin+M%22">Karin M</searchLink>; Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego (UCSD), La Jolla, CA, USA. karinoffice@ucsd.edu.
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  Data: <searchLink fieldCode="CA" term="%22Liver+Cancer+Collaborative%22">Liver Cancer Collaborative</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Jan; Vol. 637 (8045), pp. 461-469. <i>Date of Electronic Publication: </i>2025 Jan 01.
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