Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats.

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Title: Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats.
Authors: Motooka Y; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. motooka@med.nagoya-u.ac.jp., Tanaka H; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.; Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Maeda Y; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Katabuchi M; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.; Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto City, Kumamoto, 860-8556, Japan., Mashimo T; Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Toyokuni S; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. toyokuni@med.nagoya-u.ac.jp.; Center for Low-temperature Plasma Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan. toyokuni@med.nagoya-u.ac.jp.
Source: Scientific reports [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 447. Date of Electronic Publication: 2025 Jan 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats.
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  Data: <searchLink fieldCode="AU" term="%22Motooka+Y%22">Motooka Y</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. motooka@med.nagoya-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Tanaka+H%22">Tanaka H</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.; Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Maeda+Y%22">Maeda Y</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Katabuchi+M%22">Katabuchi M</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.; Department of Obstetrics and Gynecology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto City, Kumamoto, 860-8556, Japan.<br /><searchLink fieldCode="AU" term="%22Mashimo+T%22">Mashimo T</searchLink>; Laboratory Animal Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Toyokuni+S%22">Toyokuni S</searchLink>; Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. toyokuni@med.nagoya-u.ac.jp.; Center for Low-temperature Plasma Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan. toyokuni@med.nagoya-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Jan 02; Vol. 15 (1), pp. 447. <i>Date of Electronic Publication: </i>2025 Jan 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41598-024-84184-8
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              Text: 2025 Jan 02
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