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Downregulation of PAX1 in OSCC Enhances Stemness and Immunosuppression via IFIT1 and PD-L1 Pathways.

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Title: Downregulation of PAX1 in OSCC Enhances Stemness and Immunosuppression via IFIT1 and PD-L1 Pathways.
Authors: Ko HH; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Dentistry, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan., Peng HH; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Dentistry, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan., Chou HE; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Hou HH; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Liu WW; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Kuo MY; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Lee AY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan., Kao HF; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Institute of Oncology, National Taiwan University, Taipei, Taiwan., Lin HY; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan., Chang YC; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Kuo WT; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan., Cheng SJ; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Source: Oral diseases [Oral Dis] 2025 Jul; Vol. 31 (7), pp. 2071-2083. Date of Electronic Publication: 2025 Jan 02.
Publication Type: Journal Article
Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9508565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1601-0825 (Electronic) Linking ISSN: 1354523X NLM ISO Abbreviation: Oral Dis Subsets: MEDLINE
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  Data: Downregulation of PAX1 in OSCC Enhances Stemness and Immunosuppression via IFIT1 and PD-L1 Pathways.
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  Data: <searchLink fieldCode="AU" term="%22Ko+HH%22">Ko HH</searchLink>; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Dentistry, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+HH%22">Peng HH</searchLink>; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Department of Dentistry, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+HE%22">Chou HE</searchLink>; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hou+HH%22">Hou HH</searchLink>; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+WW%22">Liu WW</searchLink>; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+MY%22">Kuo MY</searchLink>; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+AY%22">Lee AY</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kao+HF%22">Kao HF</searchLink>; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; Institute of Oncology, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HY%22">Lin HY</searchLink>; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+YC%22">Chang YC</searchLink>; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+WT%22">Kuo WT</searchLink>; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+SJ%22">Cheng SJ</searchLink>; Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.; School of Dentistry, National Taiwan University, Taipei, Taiwan.; Department of Dentistry, College of Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Munksgaard%22">Munksgaard </searchLink><i>Country of Publication: </i>Denmark <i>NLM ID: </i>9508565 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1601-0825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221354523X%22">1354523X </searchLink><i>NLM ISO Abbreviation: </i>Oral Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1111/odi.15225
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      – Code: eng
        Text: English
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        StartPage: 2071
    Titles:
      – TitleFull: Downregulation of PAX1 in OSCC Enhances Stemness and Immunosuppression via IFIT1 and PD-L1 Pathways.
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              Text: 2025 Jul
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