Blood DNA virome associates with autoimmune diseases and COVID-19.
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| Title: | Blood DNA virome associates with autoimmune diseases and COVID-19. |
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| Authors: | Sasa N; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Kojima S; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences and RIKEN Cluster for Pioneering Research, Yokohama, Japan., Koide R; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences and RIKEN Cluster for Pioneering Research, Yokohama, Japan., Hasegawa T; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan., Namkoong H; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan., Hirota T; Division of Molecular Genetics, Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan., Watanabe R; Department of Integrative Medicine for Allergic and Immunological Diseases, Osaka University Graduate School of Meidince, Suita, Japan.; Department of Dermatology, University of Tsukuba, Tsukuba, Japan., Nakamura Y; Department of Dermatology, Chiba University Graduate School of Medicine, Chiba, Japan.; Cutaneous Immunology, Immunology Frontier Research Center, Osaka University, Suita, Japan., Oguro-Igashira E; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory of Immune Regulation, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Ogawa K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan., Yata T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan., Sonehara K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Yamamoto K; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan.; Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan., Kishikawa T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan., Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Divisions of Genetics and Rheumatology, Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Edahiro R; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Shirai Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan., Maeda Y; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory of Immune Regulation, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Nii T; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory of Immune Regulation, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Chubachi S; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan., Tanaka H; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan., Yabukami H; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences and RIKEN Cluster for Pioneering Research, Yokohama, Japan., Suzuki A; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Nakajima K; Department of Dermatology, Kochi Medical School, Kochi University, Nankoku, Japan., Arase N; Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan., Okamoto T; Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan., Nishikawa R; Division of Dermatology, Department of Internal Related, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Namba S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Naito T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Miyagawa I; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Tanaka H; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Ueno M; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Ishitsuka Y; Department of Integrative Medicine for Allergic and Immunological Diseases, Osaka University Graduate School of Meidince, Suita, Japan.; Department of Dermatology, University of Tsukuba, Tsukuba, Japan., Furuta J; Department of Dermatology, University of Tsukuba, Tsukuba, Japan., Kunimoto K; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan., Kajihara I; Department of Dermatology and Plastic Surgery, Kumamoto University, Kumamoto, Japan., Fukushima S; Department of Dermatology and Plastic Surgery, Kumamoto University, Kumamoto, Japan., Miyachi H; Department of Dermatology, Chiba University Graduate School of Medicine, Chiba, Japan., Matsue H; Department of Dermatology, Chiba University Graduate School of Medicine, Chiba, Japan., Kamata M; Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan., Momose M; Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan., Bito T; Division of Dermatology, Department of Internal Related, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Nagai H; Division of Dermatology, Department of Internal Related, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Ikeda T; Department of Dermatology, Kobe City Hospital Organization Kobe Medical Center West Hospital, Kobe, Japan., Horikawa T; Department of Dermatology, Nishikobe Medical Center, Kobe, Japan., Adachi A; Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center, Kakogawa, Japan., Matsubara T; Matsubara Mayflower Hospital, Kato, Japan., Ikumi K; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Nishida E; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Nakagawa I; Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan., Yagita-Sakamaki M; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Laboratory of Immune Regulation, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Yoshimura M; Department of Rheumatology, NHO Osaka Minami Medical Center, Kawachinagano, Japan., Ohshima S; Department of Rheumatology, NHO Osaka Minami Medical Center, Kawachinagano, Japan., Kinoshita M; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan., Ito S; Division of Respiratory Medicine and Allergology, Department of Internal Medicine, School of Medicine, Aichi Medical University, Aichi, Japan., Arai T; Clinical Research Center, NHO Kinki Chuo Chest Medical Center, Sakai, Japan., Hirose M; Clinical Research Center, NHO Kinki Chuo Chest Medical Center, Sakai, Japan., Tanino Y; Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan., Nikaido T; Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan., Ichiwata T; Department Respiratory Medicine, Tokyo Medical University, Tokyo, Japan., Ohkouchi S; Department of Occupational Health, Tohoku University Graduate School of Medicine, Sendai, Japan., Hirano T; Hirosaki Medical Center, Hirosaki, Japan., Takada T; Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan., Tazawa R; Student Support and Health Administration Organization, Tokyo Medical and Dental University, Tokyo, Japan., Morimoto K; Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan., Takaki M; Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki University, Nagasaki, Japan., Konno S; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Suzuki M; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Tomii K; Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan., Nakagawa A; Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan., Handa T; Department of Advanced Medicine for Respiratory Failure, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Tanizawa K; Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Ishii H; Department of Respiratory Medicine, Kyorin University Faculty of Medicine, Mitaka, Japan., Ishida M; Department of Respiratory Medicine, Kyorin University Faculty of Medicine, Mitaka, Japan., Kato T; Department of Respiratory Medicine and Allergology, Kariya Toyota General Hospital, Kariya, Japan., Takeda N; Department of Respiratory Medicine and Allergology, Kariya Toyota General Hospital, Kariya, Japan., Yokomura K; Department of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara General Hospital, Hamamatsu, Japan., Matsui T; Department of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara General Hospital, Hamamatsu, Japan., Uchida A; Department of Pulmonary Medicine, Graduate School of Medical & Dental Sciences, Kagoshima University, Kagoshima, Japan., Inoue H; Department of Pulmonary Medicine, Graduate School of Medical & Dental Sciences, Kagoshima University, Kagoshima, Japan., Imaizumi K; Department of Respiratory Medicine, Fujita Health University School of Medicine, Aichi, Japan., Goto Y; Department of Respiratory Medicine, Fujita Health University School of Medicine, Aichi, Japan., Kida H; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Respiratory Medicine, National Hospital Organization Osaka Toneyama Medical Center, Toyonaka, Japan., Fujisawa T; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan., Suda T; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan., Yamada T; Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, Shizuoka, Japan., Satake Y; Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, Shizuoka, Japan., Ibata H; Department of Respiratory Medicine, National Hospital Organization Mie Chuo Medical Center, Tsu, Japan., Saigusa M; Department of Respiratory Medicine, Shizuoka General Hospital, Shizuoka, Japan., Shirai T; Department of Respiratory Medicine, Shizuoka General Hospital, Shizuoka, Japan., Hizawa N; Department of Pulmonary Medicine, Institute of Medicine, University of Tsukuba, Tsukuba, Japan., Nakata K; Division of Advanced Medical Development, Niigata University Medical and Dental Hospital, Niigata, Japan., Imafuku S; Department of Dermatology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan., Tada Y; Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan., Asano Y; Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan., Sato S; Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan., Nishigori C; Division of Dermatology, Department of Internal Related, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan., Jinnin M; Department of Dermatology, Wakayama Medical University Graduate School of Medicine, Wakayama, Japan., Ihn H; Department of Dermatology and Plastic Surgery, Kumamoto University, Kumamoto, Japan., Asahina A; Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan., Saeki H; Department of Dermatology, Nippon Medical School, Tokyo, Japan., Kawamura T; Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan., Shimada S; Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan., Katayama I; Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Pigmentation Research and Therapeutics, Osaka City University Graduate School of Medicine, Osaka, Japan., Poisner HM; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA., Mack TM; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA., Bick AG; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA., Higasa K; Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Genome Analysis, Institute of Biomedical Science, Kansai Medical University, Hirakata, Japan., Okuno T; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan., Mochizuki H; Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan., Ishii M; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.; Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan., Koike R; Health Science Research and Development Center (HeRD), Tokyo Medical and Dental University, Tokyo, Japan., Kimura A; Institute of Research, Tokyo Medical and Dental University, Tokyo, Japan., Noguchi E; Department of Medical Genetics, University of Tsukuba, Tsukuba, Japan., Sano S; Department of Dermatology, Kochi Medical School, Kochi University, Nankoku, Japan., Inohara H; Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Japan., Fujimoto M; Department of Dermatology, University of Tsukuba, Tsukuba, Japan.; Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan., Inoue Y; Clinical Research Center, NHO Kinki Chuo Chest Medical Center, Sakai, Japan., Yamaguchi E; Division of Respiratory Medicine and Allergology, Department of Internal Medicine, School of Medicine, Aichi Medical University, Aichi, Japan., Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.; Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden., Kanai T; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan., Morita A; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Matsuda F; Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Tamari M; Division of Molecular Genetics, Research Center for Medical Science, The Jikei University School of Medicine, Tokyo, Japan., Kumanogoh A; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Immunopathology, Immunology Frontier Research Center, Osaka University, Suita, Japan., Tanaka Y; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Ohmura K; Department of Rheumatology, Kobe City Medical Center General Hospital, Kobe, Japan., Fukunaga K; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan., Imoto S; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan., Miyano S; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan., Parrish NF; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences and RIKEN Cluster for Pioneering Research, Yokohama, Japan. nicholas.parrish@riken.jp., Okada Y; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan. yuki-okada@m.u-tokyo.ac.jp.; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. yuki-okada@m.u-tokyo.ac.jp.; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. yuki-okada@m.u-tokyo.ac.jp.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan. yuki-okada@m.u-tokyo.ac.jp.; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Suita, Japan. yuki-okada@m.u-tokyo.ac.jp. |
| Corporate Authors: | Japan COVID-19 Task Force |
| Source: | Nature genetics [Nat Genet] 2025 Jan; Vol. 57 (1), pp. 65-79. Date of Electronic Publication: 2025 Jan 03. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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