High levels of global hydroxymethylation predict worse overall survival in MDS patients treated with azacitidine.

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Title: High levels of global hydroxymethylation predict worse overall survival in MDS patients treated with azacitidine.
Authors: Tiso F; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands., In 't Hout FEM; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.; Department of Hematology Radboud University Medical Center Nijmegen The Netherlands., Knops R; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands., Kroeze LI; Department of Pathology Radboud University Medical Center Nijmegen The Netherlands., van Rooij A; Department of Laboratory Medicine, Laboratory for Genetic, Endocrine, and Metabolic Diseases Radboud University Medical Center Nijmegen The Netherlands., van de Loosdrecht AA; Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands., Westers TM; Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands., Langemeijer SMC; Department of Hematology Radboud University Medical Center Nijmegen The Netherlands., Preudhomme C; Department Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France., Duployez N; Department Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France., Fenaux P; Department Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France., Kosmider O; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France., Bouscary D; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France., de Graaf AO; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands., Martens JHA; Department of Molecular Biology Radboud University Nijmegen The Netherlands., van der Reijden BA; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands., Adès L; Department Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France., Fontenay M; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France., Jansen JH; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
Source: HemaSphere [Hemasphere] 2025 Jan 03; Vol. 9 (1), pp. e70034. Date of Electronic Publication: 2025 Jan 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: High levels of global hydroxymethylation predict worse overall survival in MDS patients treated with azacitidine.
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  Data: <searchLink fieldCode="AU" term="%22Tiso+F%22">Tiso F</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22In+'t+Hout+FEM%22">In 't Hout FEM</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.; Department of Hematology Radboud University Medical Center Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22Knops+R%22">Knops R</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kroeze+LI%22">Kroeze LI</searchLink>; Department of Pathology Radboud University Medical Center Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Rooij+A%22">van Rooij A</searchLink>; Department of Laboratory Medicine, Laboratory for Genetic, Endocrine, and Metabolic Diseases Radboud University Medical Center Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+de+Loosdrecht+AA%22">van de Loosdrecht AA</searchLink>; Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Westers+TM%22">Westers TM</searchLink>; Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Langemeijer+SMC%22">Langemeijer SMC</searchLink>; Department of Hematology Radboud University Medical Center Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22Preudhomme+C%22">Preudhomme C</searchLink>; Department Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France.<br /><searchLink fieldCode="AU" term="%22Duployez+N%22">Duployez N</searchLink>; Department Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France.<br /><searchLink fieldCode="AU" term="%22Fenaux+P%22">Fenaux P</searchLink>; Department Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France.<br /><searchLink fieldCode="AU" term="%22Kosmider+O%22">Kosmider O</searchLink>; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.<br /><searchLink fieldCode="AU" term="%22Bouscary+D%22">Bouscary D</searchLink>; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.<br /><searchLink fieldCode="AU" term="%22de+Graaf+AO%22">de Graaf AO</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martens+JHA%22">Martens JHA</searchLink>; Department of Molecular Biology Radboud University Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Reijden+BA%22">van der Reijden BA</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.<br /><searchLink fieldCode="AU" term="%22Adès+L%22">Adès L</searchLink>; Department Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France.<br /><searchLink fieldCode="AU" term="%22Fontenay+M%22">Fontenay M</searchLink>; Division INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.<br /><searchLink fieldCode="AU" term="%22Jansen+JH%22">Jansen JH</searchLink>; Department of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2025 Jan 03; Vol. 9 (1), pp. e70034. <i>Date of Electronic Publication: </i>2025 Jan 03 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101740619 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2572-9241 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225729241%22">25729241 </searchLink><i>NLM ISO Abbreviation: </i>Hemasphere <i>Subsets: </i>PubMed not MEDLINE
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