The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons.

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Title: The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons.
Authors: Policarpo R; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica, Beerse, Belgium.; Vlaams Instituut voor Biotechnologie-Katholieke Universiteit Leuven Center for Brain & Disease Research, Leuven, Belgium.; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Wolfs L; Vlaams Instituut voor Biotechnologie-Katholieke Universiteit Leuven Center for Brain & Disease Research, Leuven, Belgium.; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Martínez-Montero S; Janssen Biopharma, Janssen Research & Development, South San Francisco, United States of America., Vandermeulen L; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica, Beerse, Belgium., Royaux I; Discovery Sciences, Janssen Research & Development, Janssen Pharmaceutica, Beerse, Belgium., Van Peer G; Biogazelle, Zwijnaarde, Belgium., Mestdagh P; Biogazelle, Zwijnaarde, Belgium., De Strooper B; Vlaams Instituut voor Biotechnologie-Katholieke Universiteit Leuven Center for Brain & Disease Research, Leuven, Belgium.; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.; United Kingdom Dementia Research Institute, University College London, London, United Kingdom., Sierksma A; Vlaams Instituut voor Biotechnologie-Katholieke Universiteit Leuven Center for Brain & Disease Research, Leuven, Belgium.; Laboratory for the Research of Neurodegenerative Diseases, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., d'Ydewalle C; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica, Beerse, Belgium.
Source: PloS one [PLoS One] 2025 Jan 06; Vol. 20 (1), pp. e0314973. Date of Electronic Publication: 2025 Jan 06 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0314973