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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial.

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Title: MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial.
Authors: Gounder M; Memorial Sloan Kettering Cancer Center; Weill Cornell Medical College, New York, NY, USA., Johnson M; Sarah Cannon Research Institute, Nashville, TN, USA., Heist RS; Massachusetts General Hospital, Boston, MA, USA., Shapiro GI; Dana-Farber Cancer Center, Boston, MA, USA., Postel-Vinay S; Institut Gustave Roussy and U981 INSERM, Villejuif, France.; University College of London, England, UK., Wilson FH; Yale Cancer Center, New Haven, CT, USA., Garralda E; Vall d'Hebron Institute of Oncology, Barcelona, Spain., Wulf G; Beth Israel Deaconess Medical Center, Boston, MA, USA., Almon C; Agios Pharmaceuticals Inc., Cambridge, MA, USA., Nabhan S; Agios Pharmaceuticals Inc., Cambridge, MA, USA., Aguado-Fraile E; Agios Pharmaceuticals Inc., Cambridge, MA, USA., He P; Servier, Boston, USA., Romagnoli M; Servier, Gif-sur-Yvette, France., Hossain M; Agios Pharmaceuticals Inc., Cambridge, MA, USA.; Servier, Boston, USA., Narayanaswamy R; Servier, Boston, USA., Sadou-Dubourgnoux A; Servier, Gif-sur-Yvette, France., Cooper M; Agios Pharmaceuticals Inc., Cambridge, MA, USA.; Servier, Boston, USA., Askoxylakis V; Servier, Boston, USA., Burris HA; Sarah Cannon Research Institute, Nashville, TN, USA., Tabernero J; Vall d'Hebron Institute of Oncology, Barcelona, Spain. jtabernero@vhio.net.
Source: Nature communications [Nat Commun] 2025 Jan 06; Vol. 16 (1), pp. 423. Date of Electronic Publication: 2025 Jan 06.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Jan 06; Vol. 16 (1), pp. 423. <i>Date of Electronic Publication: </i>2025 Jan 06.
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