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The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force.

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Title: The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force.
Authors: Verdoux H; French Clozapine Task Force, University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France., Bittner RA; Goethe University Frankfurt, University Hospital, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Frankfurt am Main, Germany., Hasan A; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.; DZPG (German Center for Mental Health), Partner Site, Munich/Augsburg, Germany., Qubad M; Goethe University Frankfurt, University Hospital, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Frankfurt am Main, Germany., Wagner E; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.; Evidence-based Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Lepetit A; French Clozapine Task Force; ACPPA Group, Francheville, France.; Hospices Civils de Lyon, Hôpital des Charpennes, Villeurbanne, France.; Institut des Sciences Cognitives Marc Jeannerod, CNRS, Bron, France., Arrojo-Romero M; Department of Psychiatry, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain., Bachmann C; Department of Child and Adolescent Psychiatry, Ulm University, Ulm, Germany., Beex-Oosterhuis M; Department of Hospital Pharmacy, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Bogers J; Mental Health Organization Rivierduinen, Leiden, The Netherlands., Celofiga A; Department of Psychiatry, University Medical Centre Maribor, Maribor, Slovenia., Cohen D; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands.; Esdege-Reigersdaal, Heerhugowaard, The Netherlands., de Berardis D; NHS, Department of Mental Health, G. Mazzini Hospital, Teramo, Italy., de Hert M; University Psychiatric Center Katholieke Universiteit Leuven, Kortenberg, Belgium.; Department of Neurosciences, Centre for Clinical Psychiatry, Katholieke Universiteit Leuven, Leuven, Belgium.; Leuven Brain Institute, Katholieke Universiteit Leuven, Leuven, Belgium.; Antwerp Health Law and Ethics Chair, University of Antwerp, Antwerp, Belgium., de Las Cuevas C; Department of Internal Medicine, Dermatology and Psychiatry, School of Medicine, University of La Laguna, Canary Islands, Spain., Ebdrup BH; Center for Neuropsychiatric Schizophrenia Research (CNSR), Mental Health Center, Glostrup, Copenhagen University Hospital - Mental Health Services CPH, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Fountoulakis KN; 3rd Department of Psychiatry, Division of Neurosciences, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece., Guinart D; Institut de Salut Mental, Hospital del Mar, Barcelona, Spain.; Programa Recerca en Salut Mental, Hospital del Mar Research Institute, CIBERSAM, Barcelona, Spain.; The Donald and Barbara Zucker School of Medicine, Northwell Health, New York, NY, USA., Keating D; Saint John of God Hospital, Stillorgan, Co. Dublin, Dublin, Ireland., Kopeček M; National Institute of Mental Health, Klecany, Czech Republic.; Department of Psychiatry, Third Faculty of Medicine, Charles University, Prague, Czech Republic., Lally J; Department of Psychiatry, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.; Department of Psychiatry, St Vincent's Hospital Fairview, Dublin, Ireland.; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Lazáry J; Nyírő Gyula National Institute of Psychiatry and Addictions, Budapest, Hungary., Luykx JJ; Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands.; GGZ inGeest Mental Health Care, Amsterdam, The Netherlands.; Amsterdam Neuroscience (Mood, Anxiety, Psychosis, Stress & Sleep program) and Amsterdam Public Health (Mental Health program) Research Institutes, Amsterdam, The Netherlands.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience Maastricht University Medical Center, Maastricht, The Netherlands., Maronas Amigo O; Pharmacogenomics and Drug Discovery (GenDeM), Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Genomic Medicine Group, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Galician Public Foundation of Genomic Medicine (FPGMX), Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain., Molden E; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.; Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway., Nielsen J; Mental Health Centre Glostrup, Copenhagen University Hospital, Copenhagen, Denmark., O'Donoghue B; Department of Psychiatry, University College Dublin, Dublin, Ireland.; Department of Psychiatry, St Vincent's University Hospital, Dublin, Ireland., Oswald P; Department of Psychiatry, Hôpital Universitaire de Bruxelles, Bruxelles, Belgium., Radulescu FS; Center for Drug Sciences, Faculty of Pharmacy, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania., Rohde C; Department of Affective Disorders, Aarhus University, Hospital - Psychiatry, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Sagud M; Department of Psychiatry, School of Medicine, University of Zagreb, Zagreb, Croatia.; Department for Psychiatry and Psychological Medicine, University Hospital Center Zagreb, Zagreb, Croatia., Sanz EJ; Department of Physical Medicine and Pharmacology, School of Medicine, Universidad de La Laguna, Canary Islands, Spain.; Hospital Universitario de Canarias, Tenerife, Spain., Šimunović Filipčić I; Department of Psychiatry and Psychological Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.; Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia., Sommer IE; Department of Neuroscience, and Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Taipale H; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, and Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; School of Pharmacy, University of Eastern Finland, Kuopio, Finland., Tiihonen J; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, and Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; Neuroscience Center, University of Helsinki, Helsinki, Finland., Tuppurainen H; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland., Veerman S; Mental Health Services Noord-Holland-Noord, Schagen, The Netherlands.; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands., Wilkowska A; Department of Psychiatry, Medical University of Gdańsk, Gdańsk, Poland., Spina E; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy., Schulte P; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands.; Mental Health Services Noord-Holland-Noord, Alkmaar, The Netherlands.
Source: European psychiatry : the journal of the Association of European Psychiatrists [Eur Psychiatry] 2025 Jan 10; Vol. 68 (1), pp. e17. Date of Electronic Publication: 2025 Jan 10.
Publication Type: Journal Article
Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 9111820 Publication Model: Electronic Cited Medium: Internet ISSN: 1778-3585 (Electronic) Linking ISSN: 09249338 NLM ISO Abbreviation: Eur Psychiatry Subsets: MEDLINE
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  Data: The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force.
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  Data: <searchLink fieldCode="AU" term="%22Verdoux+H%22">Verdoux H</searchLink>; French Clozapine Task Force, University of Bordeaux, Inserm, Bordeaux Population Health Research Center, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Bittner+RA%22">Bittner RA</searchLink>; Goethe University Frankfurt, University Hospital, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Hasan+A%22">Hasan A</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.; DZPG (German Center for Mental Health), Partner Site, Munich/Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Qubad+M%22">Qubad M</searchLink>; Goethe University Frankfurt, University Hospital, Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+E%22">Wagner E</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, University of Augsburg, Augsburg, Germany.; Evidence-based Psychiatry and Psychotherapy, Faculty of Medicine, University of Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lepetit+A%22">Lepetit A</searchLink>; French Clozapine Task Force; ACPPA Group, Francheville, France.; Hospices Civils de Lyon, Hôpital des Charpennes, Villeurbanne, France.; Institut des Sciences Cognitives Marc Jeannerod, CNRS, Bron, France.<br /><searchLink fieldCode="AU" term="%22Arrojo-Romero+M%22">Arrojo-Romero M</searchLink>; Department of Psychiatry, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Bachmann+C%22">Bachmann C</searchLink>; Department of Child and Adolescent Psychiatry, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Beex-Oosterhuis+M%22">Beex-Oosterhuis M</searchLink>; Department of Hospital Pharmacy, Albert Schweitzer Hospital, Dordrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bogers+J%22">Bogers J</searchLink>; Mental Health Organization Rivierduinen, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Celofiga+A%22">Celofiga A</searchLink>; Department of Psychiatry, University Medical Centre Maribor, Maribor, Slovenia.<br /><searchLink fieldCode="AU" term="%22Cohen+D%22">Cohen D</searchLink>; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands.; Esdege-Reigersdaal, Heerhugowaard, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Berardis+D%22">de Berardis D</searchLink>; NHS, Department of Mental Health, G. 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Amsterdam Neuroscience (Mood, Anxiety, Psychosis, Stress & Sleep program) and Amsterdam Public Health (Mental Health program) Research Institutes, Amsterdam, The Netherlands.; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience Maastricht University Medical Center, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maronas+Amigo+O%22">Maronas Amigo O</searchLink>; Pharmacogenomics and Drug Discovery (GenDeM), Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; Genomic Medicine Group, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.; Galician Public Foundation of Genomic Medicine (FPGMX), Galician Healthcare Service (SERGAS), Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Molden+E%22">Molden E</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.; 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Department of Psychiatry, School of Medicine, University of Zagreb, Zagreb, Croatia.; Department for Psychiatry and Psychological Medicine, University Hospital Center Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Sanz+EJ%22">Sanz EJ</searchLink>; Department of Physical Medicine and Pharmacology, School of Medicine, Universidad de La Laguna, Canary Islands, Spain.; Hospital Universitario de Canarias, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Šimunović+Filipčić+I%22">Šimunović Filipčić I</searchLink>; Department of Psychiatry and Psychological Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.; Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.<br /><searchLink fieldCode="AU" term="%22Sommer+IE%22">Sommer IE</searchLink>; Department of Neuroscience, and Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Taipale+H%22">Taipale H</searchLink>; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, and Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Tiihonen+J%22">Tiihonen J</searchLink>; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.; Department of Clinical Neuroscience, Karolinska Institutet, and Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden.; Neuroscience Center, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tuppurainen+H%22">Tuppurainen H</searchLink>; Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Veerman+S%22">Veerman S</searchLink>; Mental Health Services Noord-Holland-Noord, Schagen, The Netherlands.; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wilkowska+A%22">Wilkowska A</searchLink>; Department of Psychiatry, Medical University of Gdańsk, Gdańsk, Poland.<br /><searchLink fieldCode="AU" term="%22Spina+E%22">Spina E</searchLink>; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Schulte+P%22">Schulte P</searchLink>; Dutch Clozapine Collaboration Group, Alkmaar, The Netherlands.; Mental Health Services Noord-Holland-Noord, Alkmaar, The Netherlands.
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