Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology.

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Title: Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology.
Authors: Wickenhagen A; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Flagg M; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Port JR; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.; Laboratory of Transmission Immunology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany., Yinda CK; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Goldin K; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Gallogly S; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Schulz JE; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Lutterman T; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Williamson BN; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Kaiser F; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Mukesh RK; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., van Tol S; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Smith B; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Health, Hamilton, MT, USA., van Doremalen N; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., Russell CA; Laboratory of Applied Evolutionary Biology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands., de Wit E; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. emmie.dewit@nih.gov., Munster VJ; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. vincent.munster@nih.gov.
Source: Nature communications [Nat Commun] 2025 Jan 11; Vol. 16 (1), pp. 594. Date of Electronic Publication: 2025 Jan 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology.
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  Data: <searchLink fieldCode="AU" term="%22Wickenhagen+A%22">Wickenhagen A</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Flagg+M%22">Flagg M</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Port+JR%22">Port JR</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.; Laboratory of Transmission Immunology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.<br /><searchLink fieldCode="AU" term="%22Yinda+CK%22">Yinda CK</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Goldin+K%22">Goldin K</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Gallogly+S%22">Gallogly S</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Schulz+JE%22">Schulz JE</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Lutterman+T%22">Lutterman T</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Williamson+BN%22">Williamson BN</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Kaiser+F%22">Kaiser F</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Mukesh+RK%22">Mukesh RK</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22van+Tol+S%22">van Tol S</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Smith+B%22">Smith B</searchLink>; Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22van+Doremalen+N%22">van Doremalen N</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.<br /><searchLink fieldCode="AU" term="%22Russell+CA%22">Russell CA</searchLink>; Laboratory of Applied Evolutionary Biology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Wit+E%22">de Wit E</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. emmie.dewit@nih.gov.<br /><searchLink fieldCode="AU" term="%22Munster+VJ%22">Munster VJ</searchLink>; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. vincent.munster@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Jan 11; Vol. 16 (1), pp. 594. <i>Date of Electronic Publication: </i>2025 Jan 11.
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