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Acalabrutinib in High-Risk Chronic Lymphocytic Leukaemia Naïve Patients: An Italian Multicenter Retrospective Observational Real-Life Experience.

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Title: Acalabrutinib in High-Risk Chronic Lymphocytic Leukaemia Naïve Patients: An Italian Multicenter Retrospective Observational Real-Life Experience.
Authors: Innocenti I; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy., Tomasso A; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy., Giannarelli D; Facility of Epidemiology and Biostatistics, GSTeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy., Scarfò L; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.; Medical School, Università Vita Salute San Raffaele, Milano, Italy., Murru R; Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS G. Brotzu, Cagliari, Italy., Visentin A; Hematology Unit, Department of Medicine-DIMED, University of Padua, Padova, Italy., Frustaci AM; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy., Morelli F; Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy., Vitale C; Department of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy., Mosca A; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy., Sanna A; Hematology, Department of Oncology, AOU Careggi, Firenze, Italy., Farina G; Hematology and Medical Oncology, AORN Sant'Anna e San Sebastiano, Caserta, Italy., Laureana R; Hematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy., Gentile M; Hematology Unit AO of Cosenza, Cosenza, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy., Galitzia A; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Pasquale R; SOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy., Autore F; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy., Olivieri J; SOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy., Romeo A; Hematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy., Deodato M; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy., Stirparo L; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy., Corbingi A; Hematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy., Innao V; UOC di Ematologia, Azienda Ospedaliera di rilievo nazionale di alta specializzazione, ARNAS-Garibaldi di Catania, Catania, Italy., Perutelli F; Department of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy., Martini F; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy., Sportoletti P; Department of Medicine and Surgery, Institute of Hematology, Centro di Ricerca Emato Oncologica (CREO), University of Perugia, Perugia, Italy., Fresa A; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Napoli, Italy., Del Principe MI; Hematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy., Tedeschi A; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy., Coscia M; Department of Medicine and Surgery, University of Insubria, and Hematology Division, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy., Ghia P; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.; Medical School, Università Vita Salute San Raffaele, Milano, Italy., Laurenti L; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.
Source: Hematological oncology [Hematol Oncol] 2025 Jan; Vol. 43 (1), pp. e70033.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8307268 Publication Model: Print Cited Medium: Internet ISSN: 1099-1069 (Electronic) Linking ISSN: 02780232 NLM ISO Abbreviation: Hematol Oncol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Acalabrutinib in High-Risk Chronic Lymphocytic Leukaemia Naïve Patients: An Italian Multicenter Retrospective Observational Real-Life Experience.
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  Data: <searchLink fieldCode="AU" term="%22Innocenti+I%22">Innocenti I</searchLink>; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Tomasso+A%22">Tomasso A</searchLink>; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Giannarelli+D%22">Giannarelli D</searchLink>; Facility of Epidemiology and Biostatistics, GSTeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Scarfò+L%22">Scarfò L</searchLink>; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.; Medical School, Università Vita Salute San Raffaele, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Murru+R%22">Murru R</searchLink>; Hematology and Stem Cell Transplantation Unit, Ospedale Oncologico A. Businco, ARNAS G. Brotzu, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Visentin+A%22">Visentin A</searchLink>; Hematology Unit, Department of Medicine-DIMED, University of Padua, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Frustaci+AM%22">Frustaci AM</searchLink>; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Morelli+F%22">Morelli F</searchLink>; Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy.<br /><searchLink fieldCode="AU" term="%22Vitale+C%22">Vitale C</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Mosca+A%22">Mosca A</searchLink>; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Sanna+A%22">Sanna A</searchLink>; Hematology, Department of Oncology, AOU Careggi, Firenze, Italy.<br /><searchLink fieldCode="AU" term="%22Farina+G%22">Farina G</searchLink>; Hematology and Medical Oncology, AORN Sant'Anna e San Sebastiano, Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Laureana+R%22">Laureana R</searchLink>; Hematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Gentile+M%22">Gentile M</searchLink>; Hematology Unit AO of Cosenza, Cosenza, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Galitzia+A%22">Galitzia A</searchLink>; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Pasquale+R%22">Pasquale R</searchLink>; SOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Autore+F%22">Autore F</searchLink>; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Olivieri+J%22">Olivieri J</searchLink>; SOC Clinica Ematologia, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Romeo+A%22">Romeo A</searchLink>; Hematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Deodato+M%22">Deodato M</searchLink>; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Stirparo+L%22">Stirparo L</searchLink>; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Corbingi+A%22">Corbingi A</searchLink>; Hematology and Stem Cell Transplantation Unit, S.M. Goretti Hospital, Polo Universitario Pontino, Latina, Italy.<br /><searchLink fieldCode="AU" term="%22Innao+V%22">Innao V</searchLink>; UOC di Ematologia, Azienda Ospedaliera di rilievo nazionale di alta specializzazione, ARNAS-Garibaldi di Catania, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Perutelli+F%22">Perutelli F</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino and Division of Hematology, University Hospital (A.O.U.) Città della Salute e della Scienza di Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Martini+F%22">Martini F</searchLink>; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Sportoletti+P%22">Sportoletti P</searchLink>; Department of Medicine and Surgery, Institute of Hematology, Centro di Ricerca Emato Oncologica (CREO), University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Fresa+A%22">Fresa A</searchLink>; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Principe+MI%22">Del Principe MI</searchLink>; Hematology, Department of Biomedicine and Prevention Tor Vergata, University of Rome, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Tedeschi+A%22">Tedeschi A</searchLink>; Department of Hematology, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Coscia+M%22">Coscia M</searchLink>; Department of Medicine and Surgery, University of Insubria, and Hematology Division, ASST Sette Laghi, Ospedale di Circolo, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Ghia+P%22">Ghia P</searchLink>; Strategic Research Program on CLL, IRCSS San Raffaele, Milano, Italy.; Medical School, Università Vita Salute San Raffaele, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Laurenti+L%22">Laurenti L</searchLink>; Department of Laboratory and Haematological Sciences, Haematology Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.; Hematology Section, Department of Radiological and Hematological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.
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