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Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage.

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Title: Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage.
Authors: Kim JE; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim HS; College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon-si, Gyeonggi-do, Republic of Korea., Kim W; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee EH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim S; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim T; College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon-si, Gyeonggi-do, Republic of Korea., Shin EA; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Pyo KH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee H; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Jin SH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee JH; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Byeon SM; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Kim DJ; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Jeong J; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee J; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Ohn M; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Lee H; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea., Yu SJ; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea., Shin D; College of Pharmacy, Gachon University, Incheon, Republic of Korea., Kim S; Microbiome Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Yoo JY; CHA Advanced Research Institute, Seongnam-si, Gyeonggi-do, Republic of Korea., Lee SC; CHA Advanced Research Institute, Seongnam-si, Gyeonggi-do, Republic of Korea., Suh YG; College of Pharmacy and Institute of Pharmaceutical Sciences, CHA University, Pocheon-si, Gyeonggi-do, Republic of Korea. ygsuh@cha.ac.kr., Lee JW; Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul, Republic of Korea. jwl@snu.ac.kr.; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Republic of Korea. jwl@snu.ac.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Jan 20; Vol. 10 (1), pp. 15. Date of Electronic Publication: 2025 Jan 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
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