Targeting aldolase A in hepatocellular carcinoma leads to imbalanced glycolysis and energy stress due to uncontrolled FBP accumulation. - Snaebjornsson MT; Poeller P; Komkova D; Röhrig F; Schlicker L; Winkelkotte AM; Chaves-Filho AB; Al-Shami KM; Caballero CD; Koltsaki I; Vogel FCE; Frias-Soler RC; et al. (Nature metabolism, 2025)