RELMβ sets the threshold for microbiome-dependent oral tolerance.
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| Title: | RELMβ sets the threshold for microbiome-dependent oral tolerance. |
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| Authors: | Stephen-Victor E; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Kuziel GA; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA., Martinez-Blanco M; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Jugder BE; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Bioscience Immunology, Research and Early Development, Respiratory and Immunology, Biopharmaceuticals R&D, AstraZeneca, Waltham, MA, USA., Benamar M; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Wang Z; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Chen Q; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Lozano GL; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA., Abdel-Gadir A; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Cui Y; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Fong J; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Saint-Denis E; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA., Chang I; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA, USA., Nadeau KC; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Phipatanakul W; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Zhang A; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Farraj FA; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Holder-Niles F; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of General Pediatrics, Boston Children's Hospital, Boston, MA, USA., Zeve D; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA., Breault DT; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA., Schmitz-Abe K; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Division of Neonatology, Department of Pediatrics, University of Miami Miller School of Medicine and Holtz Children's Hospital, Jackson Health System, Miami, FL, USA., Rachid R; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Crestani E; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Rakoff-Nahoum S; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. seth.rakoff-nahoum@childrens.harvard.edu.; Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA. seth.rakoff-nahoum@childrens.harvard.edu.; Department of Microbiology, Harvard Medical School, Boston, MA, USA. seth.rakoff-nahoum@childrens.harvard.edu.; Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA. seth.rakoff-nahoum@childrens.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. seth.rakoff-nahoum@childrens.harvard.edu., Chatila TA; Division of Immunology, Boston Children's Hospital, Boston, MA, USA. talal.chatila@childrens.harvard.edu.; Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA. talal.chatila@childrens.harvard.edu. |
| Source: | Nature [Nature] 2025 Feb; Vol. 638 (8051), pp. 760-768. Date of Electronic Publication: 2025 Jan 22. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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