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Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles.

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Title: Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles.
Authors: Castagnino PA; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Haas DA; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Musante L; University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA., Tancler NA; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Tran BV; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Kean R; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Steck AR; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Martinez LA; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Mostaghel EA; Geriatric Research, Education and Clinical Center, U.S. Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA., Hooper DC; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA., Kim FJ; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.
Source: Cancer biology & therapy [Cancer Biol Ther] 2025 Dec; Vol. 26 (1), pp. 2455722. Date of Electronic Publication: 2025 Jan 26.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137842 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1555-8576 (Electronic) Linking ISSN: 15384047 NLM ISO Abbreviation: Cancer Biol Ther Subsets: MEDLINE
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  Data: Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles.
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  Data: <searchLink fieldCode="AU" term="%22Castagnino+PA%22">Castagnino PA</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Haas+DA%22">Haas DA</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Musante+L%22">Musante L</searchLink>; University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tancler+NA%22">Tancler NA</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tran+BV%22">Tran BV</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kean+R%22">Kean R</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Steck+AR%22">Steck AR</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+LA%22">Martinez LA</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mostaghel+EA%22">Mostaghel EA</searchLink>; Geriatric Research, Education and Clinical Center, U.S. Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hooper+DC%22">Hooper DC</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+FJ%22">Kim FJ</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center at Jefferson, Philadelphia, PA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101137842%22">Cancer biology & therapy</searchLink> [Cancer Biol Ther] 2025 Dec; Vol. 26 (1), pp. 2455722. <i>Date of Electronic Publication: </i>2025 Jan 26.
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              Text: 2025 Dec
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