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Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma.

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Title: Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma.
Authors: Cheng Y; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Chen X; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China., Feng L; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China., Yang Z; Department of Analytical Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Xiao L; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China., Xiang B; Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Shanghai, China., Wang X; School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, China., Liu D; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China., Lin P; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China., Shi J; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Song G; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Qian W; School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, China., Zhang B; School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, China., Xu Y; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Gao Z; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Chen L; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Wu Y; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Ma J; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Lin Y; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Zhao H; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Peng L; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China., Mao X; BGI Research, Qingdao, Shandong, China., Liu Y; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China., Hou H; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China., Yang M; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China., Ji Y; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China., Wang X; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Zhou J; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China., Xu X; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI Research, Shenzhen, Guangdong, China., Liu X; School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, China., Wei W; Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Shanghai, China., Zhang X; The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology & Immunology, Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai, China., Gao Q; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. gaoqiang@fudan.edu.cn., Zhou H; Department of Analytical Chemistry, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. zhouhu@simm.ac.cn.; University of Chinese Academy of Sciences, Beijing, China. zhouhu@simm.ac.cn., Sun Y; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China. ydsun@ion.ac.cn., Wu K; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China. wukui@genomics.cn.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China. wukui@genomics.cn.; Institute of Intelligent Medical Research (IIMR), BGI Genomics, Shenzhen, Guangdong, China. wukui@genomics.cn., Fan J; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China. fan.jia@zs-hospital.sh.cn.
Source: Cell discovery [Cell Discov] 2025 Jan 28; Vol. 11 (1), pp. 1. Date of Electronic Publication: 2025 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101661034 Publication Model: Electronic Cited Medium: Print ISSN: 2056-5968 (Print) Linking ISSN: 20565968 NLM ISO Abbreviation: Cell Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; Department of Liver Surgery and Transplantation, and Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Feng+L%22">Feng L</searchLink>; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; 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HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Mao+X%22">Mao X</searchLink>; BGI Research, Qingdao, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; Guangdong Provincial Key Laboratory of Human Disease Genomics, BGI Research, Shenzhen, Guangdong, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Hou+H%22">Hou H</searchLink>; HIM-BGI Omics Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences (CAS), BGI Research, Hangzhou, Zhejiang, China.; 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