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Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma.

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Title: Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma.
Authors: Till JE; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Seewald NJ; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Yazdani Z; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Wang Z; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Ballinger D; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Samberg H; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Dandu S; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Macia C; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Yin M; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Abdalla A; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Prior T; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Shah SS; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Patel T; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., McCoy E; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Mansour M; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Wills CA; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania., Bochenek V; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Serrano J; Department of Pathology, New York University School of Medicine, New York, New York., Snuderl M; Department of Pathology, New York University School of Medicine, New York, New York., Phillips RE; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., O'Rourke DM; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Amankulor NM; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Nabavizadeh A; Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Desai AS; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania., Gollomp K; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Binder ZA; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Zhou W; Center for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Bagley SJ; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania., Carpenter EL; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Apr 01; Vol. 31 (7), pp. 1292-1304.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
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  Data: Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Till+JE%22">Till JE</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Seewald+NJ%22">Seewald NJ</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Yazdani+Z%22">Yazdani Z</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Ballinger+D%22">Ballinger D</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Samberg+H%22">Samberg H</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Dandu+S%22">Dandu S</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Macia+C%22">Macia C</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Yin+M%22">Yin M</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Abdalla+A%22">Abdalla A</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Prior+T%22">Prior T</searchLink>; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Shah+SS%22">Shah SS</searchLink>; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Patel+T%22">Patel T</searchLink>; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22McCoy+E%22">McCoy E</searchLink>; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Mansour+M%22">Mansour M</searchLink>; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Wills+CA%22">Wills CA</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Bochenek+V%22">Bochenek V</searchLink>; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Serrano+J%22">Serrano J</searchLink>; Department of Pathology, New York University School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Snuderl+M%22">Snuderl M</searchLink>; Department of Pathology, New York University School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Phillips+RE%22">Phillips RE</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22O'Rourke+DM%22">O'Rourke DM</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Amankulor+NM%22">Amankulor NM</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Nabavizadeh+A%22">Nabavizadeh A</searchLink>; Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Desai+AS%22">Desai AS</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Gollomp+K%22">Gollomp K</searchLink>; Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Binder+ZA%22">Binder ZA</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.; Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Center for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Bagley+SJ%22">Bagley SJ</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Carpenter+EL%22">Carpenter EL</searchLink>; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania.; Division of Hematology and Oncology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
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